GSTA3 Antibody - #DF12624
| 製品: | GSTA3 Antibody |
| カタログ: | DF12624 |
| タンパク質の説明: | Rabbit polyclonal antibody to GSTA3 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 分子量: | 25 kDa; 25kD(Calculated). |
| ユニプロット: | Q16772 |
| RRID: | AB_2845586 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12624, RRID:AB_2845586.
折りたたみ／展開
Glutathione S alkyltransferase A3; Glutathione S aralkyltransferase A3; Glutathione S aryltransferase A3; Glutathione S transferase A3 3; Glutathione S transferase A3; glutathione S transferase A3 subunit; Glutathione S transferase alpha 3; Glutathione S transferase alpha type (Ya); glutathione S transferase Yc 1; glutathione S transferase Yc1 subunit; Glutathione S-transferase A3; Glutathione S-transferase A3-3; Glutathione S-transferase Ya3; Glutathione S-transferase Yc; glutathione transferase A3 subunit; Glutathione transferase alpha 3; GST 2 2; GST AA; GST class alpha; GST class alpha member 3; GST class-alpha member 3; GST Yc1; GSTA 3; GSTA3 3; Gsta3; GSTA3-3; GSTA3_HUMAN; Gstyc; GTA 3; GTA3; MGC22232; S (hydroxyalkyl)glutathione lyase A3; Yc1;
免疫原
- Q16772 GSTA3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
PTMs - Q16772 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S49 | Phosphorylation | Uniprot | |
| Y74 | Phosphorylation | Uniprot | |
| S77 | Phosphorylation | Uniprot | |
| Y79 | Phosphorylation | Uniprot | |
| Y82 | Phosphorylation | Uniprot | |
| K84 | Acetylation | Uniprot | |
| K87 | Acetylation | Uniprot | |
| K125 | Ubiquitination | Uniprot | |
| S142 | Phosphorylation | Uniprot | |
| Y147 | Phosphorylation | Uniprot | |
| K152 | Acetylation | Uniprot | |
| S154 | Phosphorylation | Uniprot | |
| S189 | Phosphorylation | Uniprot | |
| T193 | Phosphorylation | Uniprot | |
| K195 | Acetylation | Uniprot | |
| K196 | Acetylation | Uniprot | |
| S202 | Phosphorylation | Uniprot |
研究背景
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes isomerization reactions that contribute to the biosynthesis of steroid hormones. Efficiently catalyze obligatory double-bond isomerizations of delta(5)-androstene-3,17-dione and delta(5)-pregnene-3,20-dione, precursors to testosterone and progesterone, respectively.
Cytoplasm.
Homodimer.
Belongs to the GST superfamily. Alpha family.
研究領域
· Human Diseases > Drug resistance: Antineoplastic > Platinum drug resistance.
· Human Diseases > Cancers: Overview > Pathways in cancer. (View pathway)
· Human Diseases > Cancers: Overview > Chemical carcinogenesis.
· Human Diseases > Cancers: Specific types > Hepatocellular carcinoma. (View pathway)
· Metabolism > Metabolism of other amino acids > Glutathione metabolism.
· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - cytochrome P450.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.
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For Research Use Only.
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