GSTM5 Antibody - #DF12625
| 製品: | GSTM5 Antibody |
| カタログ: | DF12625 |
| タンパク質の説明: | Rabbit polyclonal antibody to GSTM5 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 分子量: | 26 kDa; 26kD(Calculated). |
| ユニプロット: | P46439 |
| RRID: | AB_2845587 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12625, RRID:AB_2845587.
折りたたみ／展開
Glutathione S alkyltransferase M5; Glutathione S aralkyltransferase M5; Glutathione S aryltransferase M5; Glutathione S transferase M5; Glutathione S transferase Mu 5; Glutathione S-transferase Mu 5; GST class mu 5; GST class-mu 5; GSTM 5; GSTM5 5; Gstm5; GSTM5-5; GSTM5_HUMAN; GTM 5; GTM5; OTTHUMP00000013359; OTTHUMP00000013361; S (hydroxyalkyl)glutathione lyase M5;
免疫原
- P46439 GSTM5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLNLKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK
PTMs - P46439 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y41 | Phosphorylation | Uniprot | |
| K50 | Ubiquitination | Uniprot | |
| K52 | Ubiquitination | Uniprot | |
| T71 | Phosphorylation | Uniprot | |
| R78 | Methylation | Uniprot | |
| K83 | Ubiquitination | Uniprot | |
| K94 | Ubiquitination | Uniprot | |
| K126 | Acetylation | Uniprot | |
| K126 | Ubiquitination | Uniprot | |
| K134 | Ubiquitination | Uniprot | |
| K136 | Ubiquitination | Uniprot | |
| K144 | Ubiquitination | Uniprot | |
| K199 | Ubiquitination | Uniprot |
研究背景
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Cytoplasm.
Homodimer.
Belongs to the GST superfamily. Mu family.
研究領域
· Human Diseases > Drug resistance: Antineoplastic > Platinum drug resistance.
· Human Diseases > Cancers: Overview > Pathways in cancer. (View pathway)
· Human Diseases > Cancers: Overview > Chemical carcinogenesis.
· Human Diseases > Cancers: Specific types > Hepatocellular carcinoma. (View pathway)
· Metabolism > Metabolism of other amino acids > Glutathione metabolism.
· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - cytochrome P450.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.