MCCC2 Antibody - #DF12655
| 製品: | MCCC2 Antibody |
| カタログ: | DF12655 |
| タンパク質の説明: | Rabbit polyclonal antibody to MCCC2 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 61 kDa; 61kD(Calculated). |
| ユニプロット: | Q9HCC0 |
| RRID: | AB_2845617 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12655, RRID:AB_2845617.
折りたたみ／展開
3 methylcrotonyl CoA carboxylase 2; 3 methylcrotonyl CoA carboxylase non biotin containing subunit; 3 methylcrotonyl CoA:carbon dioxide ligase subunit beta; 3-methylcrotonyl-CoA carboxylase 2; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta; Biotin carboxylase; MCCase subunit beta; MCCB; MCCB_HUMAN; MCCC 2; Mccc2; Methylcrotonoyl CoA carboxylase 2 (beta); Methylcrotonoyl CoA carboxylase beta chain mitochondrial; Methylcrotonoyl Coenzyme A carboxylase 2 (beta); Methylcrotonoyl-CoA carboxylase beta chain; mitochondrial; Non biotin containing subunit of 3 methylcrotonyl CoA carboxylase;
免疫原
- Q9HCC0 MCCB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MWAVLRLALRPCARASPAGPRAYHGDSVASLGTQPDLGSALYQENYKQMKALVNQLHERVEHIKLGGGEKARALHISRGKLLPRERIDNLIDPGSPFLELSQFAGYQLYDNEEVPGGGIITGIGRVSGVECMIIANDATVKGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGAYLPRQADVFPDRDHFGRTFYNQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIFLAGPPLVKAATGEEVSAEDLGGADLHCRKSGVSDHWALDDHHALHLTRKVVRNLNYQKKLDVTIEPSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTGFARIFGYPVGIVGNNGVLFSESAKKGTHFVQLCCQRNIPLLFLQNITGFMVGREYEAEGIAKDGAKMVAAVACAQVPKITLIIGGSYGAGNYGMCGRAYSPRFLYIWPNARISVMGGEQAANVLATITKDQRAREGKQFSSADEAALKEPIIKKFEEEGNPYYSSARVWDDGIIDPADTRLVLGLSFSAALNAPIEKTDFGIFRM
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9HCC0 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K50 | Ubiquitination | Uniprot | |
| K64 | Ubiquitination | Uniprot | |
| K70 | Ubiquitination | Uniprot | |
| Y145 | Phosphorylation | Uniprot | |
| R188 | Methylation | Uniprot | |
| C267 | S-Nitrosylation | Uniprot | |
| K269 | Ubiquitination | Uniprot | |
| K298 | Ubiquitination | Uniprot | |
| K326 | Acetylation | Uniprot | |
| S342 | Phosphorylation | Uniprot | |
| K382 | Acetylation | Uniprot | |
| K383 | Acetylation | Uniprot | |
| K420 | Acetylation | Uniprot | |
| K420 | Ubiquitination | Uniprot | |
| K424 | Ubiquitination | Uniprot | |
| S471 | Phosphorylation | Uniprot | |
| T484 | Phosphorylation | Uniprot | |
| T486 | Phosphorylation | Uniprot | |
| K495 | Ubiquitination | Uniprot | |
| S498 | Phosphorylation | Uniprot | |
| S499 | Phosphorylation | Uniprot | |
| K506 | Ubiquitination | Uniprot | |
| K511 | Ubiquitination | Uniprot | |
| K512 | Ubiquitination | Uniprot | |
| Y520 | Phosphorylation | Uniprot | |
| T537 | Phosphorylation | Uniprot | |
| R562 | Methylation | Uniprot |
研究背景
Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.
Mitochondrion matrix.
Probably a dodecamer composed of six biotin-containing alpha subunits (MCCC1) and six beta (MCCC2) subunits.
Belongs to the AccD/PCCB family.
研究領域
· Metabolism > Amino acid metabolism > Valine, leucine and isoleucine degradation.
· Metabolism > Global and overview maps > Metabolic pathways.
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