POPDC3 Antibody - #DF12702

(1)   (2)  
製品: POPDC3 Antibody
カタログ: DF12702
タンパク質の説明: Rabbit polyclonal antibody to POPDC3
アプリケーション: WB
反応性: Human, Mouse, Rat
予測: Bovine
分子量: 40-60kD; 34kD(Calculated).
ユニプロット: Q9HBV1
RRID: AB_2845663

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Bovine(89%)
クローナリティ:
Polyclonal
特異性:
POPDC3 Antibody detects endogenous levels of total POPDC3.
RRID:
AB_2845663
引用形式: Affinity Biosciences Cat# DF12702, RRID:AB_2845663.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

bA355M14.1; POP3; POPD3; POPD3_HUMAN; POPDC3; Popeye domain containing 3; Popeye domain containing protein 3; Popeye domain-containing protein 3; Popeye protein 3; RP11-99L11.2;

免疫原

免疫原:

A synthesized peptide derived from human POPDC3, corresponding to a region within C-terminal amino acids.

Uniprot:

Q9HBV1(POPD3_HUMAN) >>Visit HPA database.

遺伝子(ID):
POPDC3(64208)
発現特異性:
Q9HBV1 POPD3_HUMAN:

Expressed predominantly in skeletal muscle and detected in heart.

タンパク質配列:
MERNSSLWKNLIDEHPVCTTWKQEAEGAIYHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLCSAVWAWVDVCAADIFSWNFVLFVICFMQFVHIAYQVRSITFAREFQVLYSSLFQPLGISLPVFRTIALSSEVVTLEKEHCYAMQGKTSIDKLSLLVSGRIRVTVDGEFLHYIFPLQFLDSPEWDSLRPTEEGIFQVTLTAETDCRYVSWRRKKLYLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKRYHYDIRLPNFYQMSTPEIRRSPLTQHFQNSRRYCDK

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
89
Dog
78
Rabbit
78
Pig
67
Horse
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

May play a role in the maintenance of heart function mediated, at least in part, through cAMP-binding.

細胞の位置付け:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed predominantly in skeletal muscle and detected in heart.

タンパク質ファミリー:

Belongs to the popeye family.

参考文献

1). A novel splice site variant in the POPDC3 causes autosomal recessive limb‐girdle muscular dystrophy type 26. Clinical Genetics, 2022 (PubMed: 35842834) [IF=2.9]

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