Syntaxin7 Antibody - #DF12762
| 製品: | Syntaxin7 Antibody |
| カタログ: | DF12762 |
| タンパク質の説明: | Rabbit polyclonal antibody to Syntaxin7 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 35 kDa; 30kD(Calculated). |
| ユニプロット: | O15400 |
| RRID: | AB_2845723 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12762, RRID:AB_2845723.
折りたたみ／展開
STX7; STX7_HUMAN; Syn7; Syntaxin-7;
免疫原
Highest expression is found in placenta followed by heart, skeletal muscle, kidney and brain. Low expression is found in pancreas, lung and liver.
- O15400 STX7_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSYTPGVGGDPAQLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQQLQQKQQYTNQLAKETDKYIKEFGSLPTTPSEQRQRKIQKDRLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSRVSGSFPEDSSKERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTLCIIILILVIGVAIISLIIWGLNH
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O15400 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| Y3 | Phosphorylation | Uniprot | |
| T4 | Phosphorylation | Uniprot | |
| K24 | Ubiquitination | Uniprot | |
| C28 | S-Nitrosylation | Uniprot | |
| T41 | Phosphorylation | Uniprot | |
| S45 | Phosphorylation | Uniprot | |
| K55 | Ubiquitination | Uniprot | |
| K71 | Ubiquitination | Uniprot | |
| S75 | Phosphorylation | Uniprot | |
| T78 | Phosphorylation | Uniprot | |
| T79 | Phosphorylation | Uniprot | |
| S81 | Phosphorylation | Uniprot | |
| K87 | Acetylation | Uniprot | |
| K90 | Acetylation | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| S125 | Phosphorylation | Uniprot | |
| S126 | Phosphorylation | Uniprot | |
| S129 | Phosphorylation | Uniprot | |
| S131 | Phosphorylation | Uniprot | |
| S136 | Phosphorylation | Uniprot | |
| K138 | Ubiquitination | Uniprot | |
| S144 | Phosphorylation | Uniprot | |
| T149 | Phosphorylation | Uniprot | |
| T161 | Phosphorylation | Uniprot | |
| S173 | Phosphorylation | Uniprot | |
| S205 | Phosphorylation | Uniprot |
研究背景
May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes.
Early endosome membrane>Single-pass type IV membrane protein.
Highest expression is found in placenta followed by heart, skeletal muscle, kidney and brain. Low expression is found in pancreas, lung and liver.
Forms a SNARE complex with VTI1B, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Component of the SNARE complex composed of STX7, STX8, VAMP7 and VTI1B that is required for heterotypic fusion of late endosomes with lysosomes (By similarity). Interacts with VPS11, VPS16 and VPS18. Interacts with VPS33A.
Belongs to the syntaxin family.
研究領域
· Cellular Processes > Transport and catabolism > Phagosome. (View pathway)
· Genetic Information Processing > Folding, sorting and degradation > SNARE interactions in vesicular transport.
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