製品: UMPS Antibody
カタログ: DF12790
タンパク質の説明: Rabbit polyclonal antibody to UMPS
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Rabbit, Dog, Chicken
分子量: 52 kDa; 52kD(Calculated).
ユニプロット: P11172
RRID: AB_2845751

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(90%), Horse(90%), Rabbit(90%), Dog(100%), Chicken(80%)
クローナリティ:
Polyclonal
特異性:
UMPS Antibody detects endogenous levels of total UMPS.
RRID:
AB_2845751
引用形式: Affinity Biosciences Cat# DF12790, RRID:AB_2845751.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

ODC; OMPdecase; OPRT; OPRTase; Orotate phosphoribosyl transferase and orotidine 5' decarboxylase; Orotate phosphoribosyltransferase; Orotate phosphoribosyltransferase phosphoribosyltransferase; Orotidine 5' phosphate decarboxylase; Orotidine 5''-phosphate decarboxylase; RP11-71H17.9; UMP synthase; Umps; UMPS_HUMAN; Uridine 5' monophosphate synthase; Uridine monophosphate synthetase;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MAVARAALGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRPRLLSQVADILFQTAQNAGISFDTVCGVPYTALPLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGETCLIIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKMLEILEQQKKVDAETVGRVKRFIQENVFVAANHNGSPLSIKEAPKELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLGV

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Dog
100
Horse
90
Bovine
90
Rabbit
90
Chicken
80
Xenopus
70
Sheep
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P11172 基板として

Site PTM Type Enzyme
A2 Acetylation
Y16 Phosphorylation
K22 Ubiquitination
K29 Ubiquitination
S34 Phosphorylation
Y37 Phosphorylation
K106 Acetylation
K145 Ubiquitination
K160 Ubiquitination
K162 Acetylation
K162 Ubiquitination
C174 S-Nitrosylation
T175 Phosphorylation
K178 Ubiquitination
K187 Ubiquitination
K188 Ubiquitination
S214 Phosphorylation
S217 Phosphorylation
K219 Ubiquitination
K223 Ubiquitination
S241 Phosphorylation
K242 Ubiquitination
K303 Ubiquitination
K314 Ubiquitination
K323 Ubiquitination
K324 Ubiquitination
K332 Ubiquitination
S335 Phosphorylation
K352 Ubiquitination
S394 Phosphorylation
K409 Ubiquitination
Y432 Phosphorylation
K441 Ubiquitination
S444 Phosphorylation
S455 Phosphorylation
R459 Methylation
Y466 Phosphorylation
K468 Ubiquitination

研究背景

サブユニット構造:

Homodimer.

タンパク質ファミリー:

In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

In the C-terminal section; belongs to the OMP decarboxylase family.

研究領域

· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.

· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.

· Metabolism > Global and overview maps > Metabolic pathways.

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