XAB2 Antibody - #DF12798
| 製品: | XAB2 Antibody |
| カタログ: | DF12798 |
| タンパク質の説明: | Rabbit polyclonal antibody to XAB2 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Monkey |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 100 kDa; 100kD(Calculated). |
| ユニプロット: | Q9HCS7 |
| RRID: | AB_2845759 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12798, RRID:AB_2845759.
折りたたみ／展開
0610041O14Rik; adapter protein ATH 55; Adapter protein ATH-55; Ath55; AV025587; Crn related protein kim1; crn-related protein kim1; DKFZp762C1015; HCNP; HCNP protein; HCRN; KIAA1177; NTC90; PP3898; Pre-mRNA-splicing factor SYF1; Protein HCNP; RNA splicing factor; SYF1; SYF1 homolog; SYF1 homolog, RNA splicing factor; SYF1 pre mRNA splicing factor; SYF1_HUMAN; Xab2; XPA binding protein 2; XPA-binding protein 2;
免疫原
- Q9HCS7 SYF1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVVMARLSRPERPDLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFKQGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYRRFLKLSPESAEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIAAKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFIARYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGLARHAMAVYERATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIKEMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPLRAQSKILFVRSDASREELAELAQQVNPEEIQLGEDEDEDEMDLEPNEVRLEQQSVPAAVFGSLKED
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9HCS7 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S8 | Phosphorylation | Uniprot | |
| K36 | Ubiquitination | Uniprot | |
| K45 | Ubiquitination | Uniprot | |
| K62 | Ubiquitination | Uniprot | |
| C66 | S-Nitrosylation | Uniprot | |
| K69 | Ubiquitination | Uniprot | |
| K174 | Ubiquitination | Uniprot | |
| Y183 | Phosphorylation | Uniprot | |
| K188 | Ubiquitination | Uniprot | |
| K212 | Ubiquitination | Uniprot | |
| K215 | Ubiquitination | Uniprot | |
| Y279 | Phosphorylation | Uniprot | |
| S315 | Phosphorylation | Uniprot | |
| K389 | Ubiquitination | Uniprot | |
| K393 | Ubiquitination | Uniprot | |
| K420 | Acetylation | Uniprot | |
| K420 | Ubiquitination | Uniprot | |
| K423 | Ubiquitination | Uniprot | |
| K458 | Ubiquitination | Uniprot | |
| Y469 | Phosphorylation | Uniprot | |
| R479 | Methylation | Uniprot | |
| K482 | Ubiquitination | Uniprot | |
| S496 | Phosphorylation | Uniprot | |
| T499 | Phosphorylation | Uniprot | |
| K539 | Ubiquitination | Uniprot | |
| K590 | Ubiquitination | Uniprot | |
| T620 | Phosphorylation | Uniprot | |
| K637 | Ubiquitination | Uniprot | |
| K654 | Ubiquitination | Uniprot | |
| K677 | Ubiquitination | Uniprot | |
| T706 | Phosphorylation | Uniprot | |
| K708 | Ubiquitination | Uniprot | |
| K721 | Ubiquitination | Uniprot | |
| Y734 | Phosphorylation | Uniprot | |
| K770 | Ubiquitination | Uniprot | |
| K794 | Ubiquitination | Uniprot | |
| S851 | Phosphorylation | Uniprot | |
| K853 | Ubiquitination | Uniprot |
研究背景
Involved in pre-mRNA splicing as component of the spliceosome. Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing.
Nucleus.
Note: Detected in the splicing complex carrying pre-mRNA.
Associates with RNA polymerase II, the TCR-specific proteins CKN1/CSA and ERCC6/CSB, and XPA. Identified in the spliceosome C complex. Component of the XAB2 complex, a multimeric protein complex composed of XAB2, PRPF19, AQR, ZNF830, ISY1, and PPIE. Identified in a pentameric intron-binding (IB) complex composed of AQR, XAB2, ISY1, ZNF830 and PPIE that is incorporated into the spliceosome as a preassembled complex. The IB complex does not contain PRPF19.
Belongs to the crooked-neck family.
研究領域
· Genetic Information Processing > Transcription > Spliceosome.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.