ABCB6 Antibody - #DF12805
| 製品: | ABCB6 Antibody |
| カタログ: | DF12805 |
| タンパク質の説明: | Rabbit polyclonal antibody to ABCB6 |
| アプリケーション: | WB IHC |
| 反応性: | Human |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 84 kDa; 94kD(Calculated). |
| ユニプロット: | Q9NP58 |
| RRID: | AB_2845766 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12805, RRID:AB_2845766.
折りたたみ／展開
ABC; ABC transporter umat; ABC14; Abcb6; ABCB6_HUMAN; ATP binding cassette sub family B member 6, mitochondrial precursor; ATP binding cassette, sub family B (MDR/TAP), member 6; ATP-binding cassette half-transporter; ATP-binding cassette sub-family B member 6; ATP-binding cassette sub-family B member 6, mitochondrial; DUH3; LAN; MCOPCB7; Mitochondrial ABC transporter 3; mitochondrial; Mt ABC transporter 3; Mt-ABC transporter 3; MTABC3; P glycoprotein related protein; P-glycoprotein-related protein; PRP; Ubiquitously expressed mammalian ABC half transporter; Ubiquitously-expressed mammalian ABC half transporter; UMAT;
免疫原
- Q9NP58 ABCB6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVTVGNYCEAEGPVGPAWMQDGLSPCFFFTLVPSTRMALGTLALVLALPCRRRERPAGADSLSWGAGPRISPYVLQLLLATLQAALPLAGLAGRVGTARGAPLPSYLLLASVLESLAGACGLWLLVVERSQARQRLAMGIWIKFRHSPGLLLLWTVAFAAENLALVSWNSPQWWWARADLGQQVQFSLWVLRYVVSGGLFVLGLWAPGLRPQSYTLQVHEEDQDVERSQVRSAAQQSTWRDFGRKLRLLSGYLWPRGSPALQLVVLICLGLMGLERALNVLVPIFYRNIVNLLTEKAPWNSLAWTVTSYVFLKFLQGGGTGSTGFVSNLRTFLWIRVQQFTSRRVELLIFSHLHELSLRWHLGRRTGEVLRIADRGTSSVTGLLSYLVFNVIPTLADIIIGIIYFSMFFNAWFGLIVFLCMSLYLTLTIVVTEWRTKFRRAMNTQENATRARAVDSLLNFETVKYYNAESYEVERYREAIIKYQGLEWKSSASLVLLNQTQNLVIGLGLLAGSLLCAYFVTEQKLQVGDYVLFGTYIIQLYMPLNWFGTYYRMIQTNFIDMENMFDLLKEETEVKDLPGAGPLRFQKGRIEFENVHFSYADGRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQDISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFPEGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAKVCANRTTIVVAHRLSTVVNADQILVIKDGCIVERGRHEALLSRGGVYADMWQLQQGQEETSEDTKPQTMER
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NP58 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T444 | Phosphorylation | Uniprot | |
| T449 | Phosphorylation | Uniprot | |
| S456 | Phosphorylation | Uniprot | |
| K464 | Ubiquitination | Uniprot | |
| K482 | Sumoylation | Uniprot | |
| K482 | Ubiquitination | Uniprot | |
| K569 | Ubiquitination | Uniprot | |
| K575 | Ubiquitination | Uniprot | |
| K726 | Ubiquitination | Uniprot | |
| K743 | Ubiquitination | Uniprot | |
| K771 | Ubiquitination | Uniprot | |
| K836 | Ubiquitination | Uniprot |
研究背景
Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.
Cell membrane>Multi-pass membrane protein. Mitochondrion outer membrane>Multi-pass membrane protein. Endoplasmic reticulum membrane>Multi-pass membrane protein. Golgi apparatus membrane>Multi-pass membrane protein. Endosome membrane>Multi-pass membrane protein.
Note: localized to the endosome-like compartment and dendrite tips.
Widely expressed. High expression is detected in the retinal epithelium.
Homodimer.
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
研究領域
· Environmental Information Processing > Membrane transport > ABC transporters.
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