ACAT2 Antibody - #DF12807
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12807, RRID:AB_2845768.
折りたたみ／展開
ACACT2; ACAT 2; ACAT2; Acyl Co A: cholesterol acyltransferase 2; Acyl CoA:cholesterol acyltransferase 2; acyl coenzyme A cholestrol acyltransferase 2; Acyl coenzyme A:cholesterol acyltransferase 2; ARGP2; Cholesterol acyltransferase 2; Sterol O acyl transferase 2; SOAT2;SOAT 2;Sterol O-acyltransferase 2;Cholesterol acyltransferase 2;
免疫原
- O75908 SOAT2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEPGGARLRLQRTEGLGGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQSYPSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHFRTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLAPYQALRLWARGTWTQATGLGCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFLMKSYSFLREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKNFAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQRTGPAWNVLMWTMLFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O75908 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T285 | Phosphorylation | Uniprot |
研究背景
Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Expression seems confined in hepatocytes and enterocytes.
May form homo- or heterodimers.
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
研究領域
· Metabolism > Lipid metabolism > Steroid biosynthesis.
· Organismal Systems > Digestive system > Cholesterol metabolism.
Restrictive clause
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