AKR7A3 Antibody - #DF12819
| 製品: | AKR7A3 Antibody |
| カタログ: | DF12819 |
| タンパク質の説明: | Rabbit polyclonal antibody to AKR7A3 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 分子量: | 37 kDa; 37kD(Calculated). |
| ユニプロット: | O95154 |
| RRID: | AB_2845780 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12819, RRID:AB_2845780.
折りたたみ／展開
AFAR 2; AFAR2; AFB1 aldehyde reductase 2; AFB1 AR 2; AFB1-AR 2; Aflatoxin aldehyde reductase; Aflatoxin B1 aldehyde reductase 2; Aflatoxin B1 aldehyde reductase member 3; Akr7a3; Aldo keto reductase family 7 member A3; ARK73_HUMAN; OTTHUMP00000002623;
免疫原
- O95154 ARK73_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVTHECPNYFR
PTMs - O95154 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S6 | Phosphorylation | Uniprot | |
| T12 | Phosphorylation | Uniprot | |
| R21 | Methylation | Uniprot | |
| T27 | Phosphorylation | Uniprot | |
| S28 | Phosphorylation | Uniprot | |
| T32 | Phosphorylation | Uniprot | |
| S85 | Phosphorylation | Uniprot | |
| S90 | Phosphorylation | Uniprot | |
| Y111 | Phosphorylation | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| S143 | Phosphorylation | Uniprot | |
| T227 | Phosphorylation | Uniprot | |
| S259 | Phosphorylation | Uniprot |
研究背景
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
Cytoplasm.
Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium.
Homodimer.
Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
研究領域
· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.
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