CHMP7 Antibody - #DF12896
| 製品: | CHMP7 Antibody |
| カタログ: | DF12896 |
| タンパク質の説明: | Rabbit polyclonal antibody to CHMP7 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 51 kDa, 75 kDa; 51kD(Calculated). |
| ユニプロット: | Q8WUX9 |
| RRID: | AB_2845857 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12896, RRID:AB_2845857.
免疫原
- Q8WUX9 CHMP7_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MWSPEREAEAPAGGDPAGLLPPEWEEDEERMSFLFSAFKRSREVNSTDWDSKMGFWAPLVLSHSRRQGVVRLRLRDLQEAFQRKGSVPLGLATVLQDLLRRGELQRESDFMASVDSSWISWGVGVFLLKPLKWTLSNMLGDNKVPAEEVLVAVELLKEKAEEVYRLYQNSPLSSHPVVALSELSTLCANSCPDERTFYLVLLQLQKEKRVTVLEQNGEKIVKFARGPRAKVSPVNDVDVGVYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRISDAELEAELEKLSLSEGGLVPSSKSPKRQLEPTLKPL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8WUX9 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S3 | Phosphorylation | Uniprot | |
| S46 | Phosphorylation | Uniprot | |
| K84 | Ubiquitination | Uniprot | |
| K219 | Ubiquitination | Uniprot | |
| K230 | Ubiquitination | Uniprot | |
| S232 | Phosphorylation | Uniprot | |
| Y242 | Phosphorylation | Uniprot | |
| K254 | Ubiquitination | Uniprot | |
| K337 | Ubiquitination | Uniprot | |
| K393 | Ubiquitination | Uniprot | |
| R405 | Methylation | Uniprot | |
| T408 | Phosphorylation | Uniprot | |
| S410 | Phosphorylation | Uniprot | |
| S417 | Phosphorylation | Uniprot | |
| K427 | Ubiquitination | Uniprot | |
| S429 | Phosphorylation | Uniprot | |
| S431 | Phosphorylation | Uniprot | |
| S438 | Phosphorylation | Uniprot | |
| S439 | Phosphorylation | Uniprot | |
| S441 | Phosphorylation | Uniprot |
研究背景
ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase. Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Plays a role in the endosomal sorting pathway.
Cytoplasm. Nucleus envelope.
Note: Diffused localization, with some punctate distribution, especially in the perinuclear area (PubMed:16856878). Localizes to the nucleus envelope during late anaphase (PubMed:26040712).
Interacts with CHMP4B, but not with VPS25.
Belongs to the SNF7 family.
研究領域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
· Cellular Processes > Cell growth and death > Necroptosis. (View pathway)
Restrictive clause
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For Research Use Only.
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