DCP1B Antibody - #DF12929
製品: | DCP1B Antibody |
カタログ: | DF12929 |
タンパク質の説明: | Rabbit polyclonal antibody to DCP1B |
アプリケーション: | WB |
反応性: | Human, Mouse, Rat |
予測: | Horse |
分子量: | 68 kDa; 68kD(Calculated). |
ユニプロット: | Q8IZD4 |
RRID: | AB_2845890 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12929, RRID:AB_2845890.
折りたたみ/展開
DCP 1B; DCP1; DCP1 decapping enzyme homolog B; DCP1B; DCP1B_HUMAN; Decapping enzyme Dcp1b; Decapping enzyme hDcp1b; Decapping enzyme homolog B (S. cerevisiae); Decapping mRNA 1B; hDcp1b; mRNA decapping enzyme 1B; mRNA-decapping enzyme 1B;
免疫原
- Q8IZD4 DCP1B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAVAAGGLVGKGRDISLAALQRHDPYINRIVDVASQVALYTFGHRANEWEKTDVEGTLFVYTRSASPKHGFTIMNRLSMENRTEPITKDLDFQLQDPFLLYRNARLSIYGIWFYDKEECQRIAELMKNLTQYEQLKAHQGTGAGISPVILNSGEGKEVDILRMLIKAKDEYTKCKTCSEPKKITSSSAIYDNPNLIKPIPVKPSENQQQRIPQPNQTLDPEPQHLSLTALFGKQDKATCQETVEPPQTLHQQQQQQQQQQEKLPIRQGVVRSLSYEEPRRHSPPIEKQLCPAIQKLMVRSADLHPLSELPENRPCENGSTHSAGEFFTGPVQPGSPHNIGTSRGVQNASRTQNLFEKLQSTPGAANKCDPSTPAPASSAALNRSRAPTSVTPVAPGKGLAQPPQAYFNGSLPPQTVGHQAHGREQSTLPRQTLPISGSQTGSSGVISPQELLKKLQIVQQEQQLHASNRPALAAKFPVLAQSSGTGKPLESWINKTPNTEQQTPLFQVISPQRIPATAAPSLLMSPMVFAQPTSVPPKERESGLLPVGGQEPPAAATSLLLPIQSPEPSVITSSPLTKLQLQEALLYLIQNDDNFLNIIYEAYLFSMTQAAMKKTM
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8IZD4 基板として
Site | PTM Type | Enzyme | Source |
---|---|---|---|
A2 | Acetylation | Uniprot | |
K12 | Ubiquitination | Uniprot | |
S67 | Phosphorylation | Uniprot | |
K69 | Ubiquitination | Uniprot | |
K89 | Ubiquitination | Uniprot | |
Y110 | Phosphorylation | Uniprot | |
K128 | Ubiquitination | Uniprot | |
Y133 | Phosphorylation | Uniprot | |
K137 | Ubiquitination | Uniprot | |
T142 | Phosphorylation | Uniprot | |
S147 | Phosphorylation | Uniprot | |
K157 | Ubiquitination | Uniprot | |
Y172 | Phosphorylation | Uniprot | |
T173 | Phosphorylation | Uniprot | |
K183 | Ubiquitination | Uniprot | |
S186 | Phosphorylation | Uniprot | |
S187 | Phosphorylation | Uniprot | |
S188 | Phosphorylation | Uniprot | |
Y191 | Phosphorylation | Uniprot | |
K198 | Ubiquitination | Uniprot | |
S227 | Phosphorylation | Uniprot | |
T229 | Phosphorylation | Uniprot | |
K234 | Ubiquitination | Uniprot | |
S275 | Phosphorylation | Uniprot | |
Y276 | Phosphorylation | Uniprot | |
S283 | Phosphorylation | Uniprot | |
S336 | Phosphorylation | Uniprot | |
K358 | Ubiquitination | Uniprot | |
T362 | Phosphorylation | Uniprot | |
S372 | Phosphorylation | Uniprot | |
T373 | Phosphorylation | Uniprot | |
S385 | Phosphorylation | Uniprot | |
T392 | Phosphorylation | Uniprot | |
S448 | Phosphorylation | Uniprot | |
K455 | Ubiquitination | Uniprot | |
K488 | Ubiquitination | Uniprot | |
T504 | Phosphorylation | Uniprot | |
S511 | Phosphorylation | Uniprot | |
S566 | Phosphorylation | Uniprot |
研究背景
May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (By similarity).
Cytoplasm. Nucleus.
Binds DCP1A. Part of a complex containing enzymes involved in mRNA decay, including DCP2, LSM1, LSM3 and CNOT6.
Belongs to the DCP1 family.
研究領域
· Genetic Information Processing > Folding, sorting and degradation > RNA degradation.
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