DHX15 Antibody - #DF12939
| 製品: | DHX15 Antibody |
| カタログ: | DF12939 |
| タンパク質の説明: | Rabbit polyclonal antibody to DHX15 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 91 kDa; 91kD(Calculated). |
| ユニプロット: | O43143 |
| RRID: | AB_2845900 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12939, RRID:AB_2845900.
折りたたみ／展開
ATP dependent RNA helicase #46; ATP-dependent RNA helicase #46; DBP1; DDX15; DEADH box 15; DEAH (Asp Glu Ala His) box polypeptide 15; DEAH box polypeptide 15; DEAH box protein 15; DHX15; DHX15_HUMAN; HRH2; Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; PRP43; PrPp43p; RNA helicase 2;
免疫原
- O43143 DHX15_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSKRHRLDLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKELRASTNAMLISAGLPPLKASHSAHSTHSAHSTHSTHSAHSTHAGHAGHTSLPQCINPFTNLPHTPRYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHPSTVLDHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQCEAKRQLDRIIAKLQSKEYSQY
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O43143 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K3 | Acetylation | Uniprot | |
| Y13 | Phosphorylation | Uniprot | |
| S15 | Phosphorylation | Uniprot | |
| K17 | Acetylation | Uniprot | |
| K17 | Ubiquitination | Uniprot | |
| K18 | Acetylation | Uniprot | |
| K18 | Methylation | Uniprot | |
| R42 | Methylation | Uniprot | |
| R44 | Methylation | Uniprot | |
| S71 | Phosphorylation | Uniprot | |
| Y128 | Phosphorylation | Uniprot | |
| K132 | Acetylation | Uniprot | |
| K132 | Ubiquitination | Uniprot | |
| Y142 | Phosphorylation | Uniprot | |
| K143 | Ubiquitination | Uniprot | |
| S155 | Phosphorylation | Uniprot | |
| T162 | Phosphorylation | Uniprot | |
| S164 | Phosphorylation | Uniprot | |
| K166 | Acetylation | Uniprot | |
| K185 | Acetylation | Uniprot | |
| C190 | S-Nitrosylation | Uniprot | |
| K230 | Ubiquitination | Uniprot | |
| K234 | Ubiquitination | Uniprot | |
| Y254 | Phosphorylation | Uniprot | |
| T266 | Phosphorylation | Uniprot | |
| S292 | Phosphorylation | Uniprot | |
| T324 | Phosphorylation | Uniprot | |
| Y331 | Phosphorylation | Uniprot | |
| K370 | Ubiquitination | Uniprot | |
| K384 | Ubiquitination | Uniprot | |
| K407 | Ubiquitination | Uniprot | |
| K445 | Acetylation | Uniprot | |
| K445 | Ubiquitination | Uniprot | |
| K463 | Ubiquitination | Uniprot | |
| T476 | Phosphorylation | Uniprot | |
| K480 | Ubiquitination | Uniprot | |
| K488 | Acetylation | Uniprot | |
| K488 | Ubiquitination | Uniprot | |
| Y490 | Phosphorylation | Uniprot | |
| K491 | Sumoylation | Uniprot | |
| K491 | Ubiquitination | Uniprot | |
| Y499 | Phosphorylation | Uniprot | |
| S505 | Phosphorylation | Uniprot | |
| S509 | Phosphorylation | Uniprot | |
| K515 | Ubiquitination | Uniprot | |
| K516 | Ubiquitination | Uniprot | |
| K614 | Ubiquitination | Uniprot | |
| Y631 | Phosphorylation | Uniprot | |
| S653 | Phosphorylation | Uniprot | |
| R670 | Methylation | Uniprot | |
| Y686 | Phosphorylation | Uniprot | |
| T695 | Phosphorylation | Uniprot | |
| Y710 | Phosphorylation | Uniprot | |
| K754 | Acetylation | Uniprot | |
| K754 | Ubiquitination | Uniprot | |
| K760 | Ubiquitination | Uniprot | |
| K777 | Ubiquitination | Uniprot | |
| K786 | Acetylation | Uniprot | |
| K786 | Ubiquitination | Uniprot | |
| K790 | Ubiquitination | Uniprot | |
| Y792 | Phosphorylation | Uniprot | |
| S793 | Phosphorylation | Uniprot | |
| Y795 | Phosphorylation | Uniprot |
研究背景
Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns.
Nucleus. Nucleus>Nucleolus.
Ubiquitous.
Interacts with SSB/La. Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Identified in the Intron Large (IL) complex, a post-mRNA release spliceosomal complex containing the excised intron, U2, U5 and U6 snRNPs, and splicing factors; the association may be transient. Interacts with TFIP11; indicative for a recruitment to the IL complex. Interacts with GPATCH2.
Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.
研究領域
· Genetic Information Processing > Transcription > Spliceosome.
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