製品: FMO5 Antibody
カタログ: DF13018
タンパク質の説明: Rabbit polyclonal antibody to FMO5
アプリケーション: WB
反応性: Human, Mouse, Rat
予測: Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
分子量: 60 kDa; 60kD(Calculated).
ユニプロット: P49326
RRID: AB_2845979

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Zebrafish(83%), Bovine(92%), Horse(83%), Sheep(92%), Rabbit(92%), Dog(92%), Xenopus(92%)
クローナリティ:
Polyclonal
特異性:
FMO5 Antibody detects endogenous levels of total FMO5.
RRID:
AB_2845979
引用形式: Affinity Biosciences Cat# DF13018, RRID:AB_2845979.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Dimethylaniline monooxygenase [N oxide forming] 5; Dimethylaniline monooxygenase [N-oxide-forming] 5; Dimethylaniline oxidase 5; FMO 5; FMO5; FMO5_HUMAN; Hepatic flavin containing monooxygenase 5; Hepatic flavin-containing monooxygenase 5;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P49326 FMO5_HUMAN:

Expressed in fetal and adult liver.

タンパク質配列:
MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWRFQENPEEGRASIYKSVIINTSKEMMCFSDYPIPDHYPNFMHNAQVLEYFRMYAKEFDLLKYIRFKTTVCSVKKQPDFATSGQWEVVTESEGKKEMNVFDGVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKVKGNVKEFTETAAIFEDGSREDDIDAVIFATGYSFDFPFLEDSVKVVKNKISLYKKVFPPNLERPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKTLPSQSEMMAEISKAQEEIDKRYVESQRHTIQGDYIDTMEELADLVGVRPNLLSLAFTDPKLALHLLLGPCTPIHYRVQGPGKWDGARKAILTTDDRIRKPLMTRVVERSSSMTSTMTIGKFMLALAFFAIIIAYF

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
92
Sheep
92
Dog
92
Xenopus
92
Rabbit
92
Horse
83
Zebrafish
83
Chicken
75
Pig
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P49326 基板として

Site PTM Type Enzyme
S54 Phosphorylation
Y56 Phosphorylation
S58 Phosphorylation
Y104 Phosphorylation
Y171 Phosphorylation
Y177 Phosphorylation
S280 Phosphorylation
T284 Phosphorylation
T398 Phosphorylation
S410 Phosphorylation
T501 Phosphorylation
S509 Phosphorylation
S512 Phosphorylation

研究背景

機能:

In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme.

細胞の位置付け:

Microsome membrane. Endoplasmic reticulum membrane.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in fetal and adult liver.

タンパク質ファミリー:

Belongs to the FMO family.

研究領域

· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - cytochrome P450.

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