FUT6 Antibody - #DF13025
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13025, RRID:AB_2845986.
折りたたみ／展開
Alpha (1,3) fucosyltransferase; EC=2.4.1.65; FCT3A; FT1A; Fuc TVI; fucosyltransferase 6 (alpha (1,3) fucosyltransferase); Fucosyltransferase 6; Fucosyltransferase VI; FucT VI; Galactoside 3 L fucosyltransferase;
免疫原
- P51993 FUT6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDPLGPAKPQWSWRCCLTTLLFQLLMAVCFFSYLRVSQDDPTVYPNGSRFPDSTGTPAHSIPLILLWTWPFNKPIALPRCSEMVPGTADCNITADRKVYPQADAVIVHHREVMYNPSAQLPRSPRRQGQRWIWFSMESPSHCWQLKAMDGYFNLTMSYRSDSDIFTPYGWLEPWSGQPAHPPLNLSAKTELVAWAVSNWGPNSARVRYYQSLQAHLKVDVYGRSHKPLPQGTMMETLSRYKFYLAFENSLHPDYITEKLWRNALEAWAVPVVLGPSRSNYERFLPPDAFIHVDDFQSPKDLARYLQELDKDHARYLSYFRWRETLRPRSFSWALAFCKACWKLQEESRYQTRGIAAWFT
PTMs - P51993 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S123 | Phosphorylation | Uniprot | |
| Y208 | Phosphorylation | Uniprot | |
| Y209 | Phosphorylation | Uniprot | |
| Y221 | Phosphorylation | Uniprot | |
| Y315 | Phosphorylation | Uniprot | |
| T324 | Phosphorylation | Uniprot |
研究背景
Enzyme involved in the biosynthesis of the E-Selectin ligand, sialyl-Lewis X. Catalyzes the transfer of fucose from GDP-beta-fucose to alpha-2,3 sialylated substrates.
Golgi apparatus>Golgi stack membrane>Single-pass type II membrane protein.
Note: Membrane-bound form in trans cisternae of Golgi.
Kidney, liver, colon, small intestine, bladder, uterus and salivary gland.
Belongs to the glycosyltransferase 10 family.
研究領域
· Metabolism > Glycan biosynthesis and metabolism > Glycosphingolipid biosynthesis - lacto and neolacto series.
· Metabolism > Global and overview maps > Metabolic pathways.
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