製品: GAMT Antibody
カタログ: DF13032
タンパク質の説明: Rabbit polyclonal antibody to GAMT
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat, Zebrafish
予測: Pig, Bovine, Horse, Dog, Chicken
分子量: 26 kDa; 26kD(Calculated).
ユニプロット: Q14353
RRID: AB_2845993

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat,Zebrafish
予測:
Pig(100%), Bovine(90%), Horse(80%), Dog(100%), Chicken(80%)
クローナリティ:
Polyclonal
特異性:
GAMT Antibody detects endogenous levels of total GAMT.
RRID:
AB_2845993
引用形式: Affinity Biosciences Cat# DF13032, RRID:AB_2845993.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

CCDS2; Epididymis secretory protein Li 20; GAMT; GAMT_HUMAN; Guanidinoacetate N methyltransferase; Guanidinoacetate N-methyltransferase; HEL-S-20; PIG2; TP53I2;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q14353 GAMT_HUMAN:

Expressed in liver.

タンパク質配列:
MSAPSATPIFAPGENCSPAWGAAPAAYDAADTHLRILGKPVMERWETPYMHALAAAASSKGGRVLEVGFGMAIAASKVQEAPIDEHWIIECNDGVFQRLRDWAPRQTHKVIPLKGLWEDVAPTLPDGHFDGILYDTYPLSEETWHTHQFNFIKNHAFRLLKPGGVLTYCNLTSWGELMKSKYSDITIMFEETQVPALLEAGFRRENIRTEVMALVPPADCRYYAFPQMITPLVTKG

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Dog
100
Bovine
90
Horse
80
Chicken
80
Xenopus
70
Zebrafish
60
Sheep
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q14353 基板として

Site PTM Type Enzyme
S2 Acetylation
S17 Phosphorylation
Y27 Phosphorylation
K39 Ubiquitination
K60 Ubiquitination
K109 Ubiquitination
Y222 Phosphorylation
Y223 Phosphorylation
K235 Ubiquitination

研究背景

機能:

Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor. Important in nervous system development.

組織特異性:

Expressed in liver.

サブユニット構造:

Monomer.

タンパク質ファミリー:

Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.

研究領域

· Metabolism > Amino acid metabolism > Glycine, serine and threonine metabolism.

· Metabolism > Amino acid metabolism > Arginine and proline metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.