製品: GGCT Antibody
カタログ: DF13037
タンパク質の説明: Rabbit polyclonal antibody to GGCT
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 21 kDa; 21kD(Calculated).
ユニプロット: O75223
RRID: AB_2845998

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(90%), Horse(100%), Sheep(90%), Rabbit(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
GGCT Antibody detects endogenous levels of total GGCT.
RRID:
AB_2845998
引用形式: Affinity Biosciences Cat# DF13037, RRID:AB_2845998.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

C7orf24; CRF21; Cytochrome c-releasing factor 21; Gamma glutamyl cyclotransferase; Gamma-glutamylcyclotransferase; GCTG; GGC; Ggct; GGCT_HUMAN;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MANSGCKDVTGPDEESFLYFAYGSNLLTERIHLRNPSAAFFCVARLQDFKLDFGNSQGKTSQTWHGGIATIFQSPGDEVWGVVWKMNKSNLNSLDEQEGVKSGMYVVIEVKVATQEGKEITCRSYLMTNYESAPPSPQYKKIICMGAKENGLPLEYQEKLKAIEPNDYTGKVSEEIEDIIKKGETQTL

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Dog
100
Rabbit
100
Bovine
90
Sheep
90
Chicken
70
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O75223 基板として

Site PTM Type Enzyme
S16 Phosphorylation
S24 Phosphorylation
S37 Phosphorylation
S93 Phosphorylation
K118 Ubiquitination
S136 Phosphorylation
K140 Ubiquitination
K141 Ubiquitination
K159 Ubiquitination
K161 Ubiquitination
Y168 Phosphorylation
S173 Phosphorylation
T187 Phosphorylation

研究背景

機能:

Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis.

サブユニット構造:

Homodimer.

タンパク質ファミリー:

Belongs to the gamma-glutamylcyclotransferase family.

研究領域

· Metabolism > Metabolism of other amino acids > Glutathione metabolism.

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