製品: HOXA10 Antibody
カタログ: DF13067
タンパク質の説明: Rabbit polyclonal antibody to HOXA10
アプリケーション: WB
反応性: Human
予測: Horse, Sheep, Dog
分子量: 50 kDa; 42kD(Calculated).
ユニプロット: P31260
RRID: AB_2846028

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Horse(100%), Sheep(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
HOXA10 Antibody detects endogenous levels of total HOXA10.
RRID:
AB_2846028
引用形式: Affinity Biosciences Cat# DF13067, RRID:AB_2846028.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Centaurin alpha 1 like; Homeo box A10; Homeobox A10; Homeobox protein 1H; Homeobox protein Hox A10; Homeobox protein Hox-1.8; Homeobox protein Hox-1H; Homeobox protein Hox-A10; Homeobox protein HOXA10; HOX 1; HOX 1.8; HOX 1H; HOX A10; HOX1; HOX1.8; HOX1H; HOXA 10; HOXA10; HOXA10 protein; HXA10_HUMAN; MGC12859; PL;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MSARKGYLLPSPNYPTTMSCSESPAANSFLVDSLISSGRGEAGGGGGGAGGGGGGGYYAHGGVYLPPAADLPYGLQSCGLFPTLGGKRNEAASPGSGGGGGGLGPGAHGYGPSPIDLWLDAPRSCRMEPPDGPPPPPQQQPPPPPQPPQPAPQATSCSFAQNIKEESSYCLYDSADKCPKVSATAAELAPFPRGPPPDGCALGTSSGVPVPGYFRLSQAYGTAKGYGSGGGGAQQLGAGPFPAQPPGRGFDLPPALASGSADAARKERALDSPPPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKDSLGNSKGENAANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFNFS

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Sheep
100
Dog
100
Pig
0
Bovine
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P31260 基板として

Site PTM Type Enzyme
S19 Phosphorylation
S93 Phosphorylation
R193 Methylation
S272 Phosphorylation
T277 Phosphorylation
S313 Phosphorylation
K323 Ubiquitination
S335 Phosphorylation
K338 Acetylation
K339 Acetylation
K339 Ubiquitination
Y343 Phosphorylation
K345 Ubiquitination
T348 Phosphorylation
Y360 Phosphorylation
R378 Methylation

研究背景

機能:

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to the DNA sequence 5'-AA[AT]TTTTATTAC-3'.

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with SIRT2; the interaction is direct.

タンパク質ファミリー:

Belongs to the Abd-B homeobox family.

研究領域

· Human Diseases > Cancers: Overview > Transcriptional misregulation in cancer.

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