KLC2 Antibody - #DF13111
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13111, RRID:AB_2846071.
折りたたみ／展開
Kinesin light chain 2; Kinesin light chain 3; KLC2; KLC2 like; KLC2-like; KLC2L; KLC3; KLC3_HUMAN; KLCt; KNS2B;
免疫原
- Q6P597 KLC3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSVQVAAPGSAGLGPERLSPEELVRQTRQVVQGLEALRAEHHGLAGHLAEALAGQGPAAGLEMLEEKQQVVSHSLEAIELGLGEAQVLLALSAHVGALEAEKQRLRSQARRLAQENVWLREELEETQRRLRASEESVAQLEEEKRHLEFLGQLRQYDPPAESQQSESPPRRDSLASLFPSEEEERKGPEAAGAAAAQQGGYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKTKNNLASAYLKQNKYQQAEELYKEILHKEDLPAPLGAPNTGTAGDAEQALRRSSSLSKIRESIRRGSEKLVSRLRGEAAAGAAGMKRAMSLNTLNVDAPRAPGTQFPSWHLDKAPRTLSASTQDLSPH
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6P597 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S10 | Phosphorylation | Uniprot | |
| S162 | Phosphorylation | Uniprot | |
| S167 | Phosphorylation | Uniprot | |
| S173 | Phosphorylation | Uniprot | |
| Y201 | Phosphorylation | Uniprot | |
| S361 | Phosphorylation | Uniprot | |
| T377 | Phosphorylation | Uniprot | |
| S383 | Phosphorylation | Uniprot | |
| Y385 | Phosphorylation | Uniprot | |
| K399 | Ubiquitination | Uniprot | |
| S429 | Phosphorylation | Uniprot | |
| S430 | Phosphorylation | Uniprot | |
| S431 | Phosphorylation | Uniprot | |
| S443 | Phosphorylation | Uniprot | |
| K462 | Methylation | Uniprot | |
| S466 | Phosphorylation | Uniprot | |
| T469 | Phosphorylation | Uniprot | |
| S495 | Phosphorylation | Uniprot | |
| S497 | Phosphorylation | Uniprot | |
| T498 | Phosphorylation | Uniprot | |
| S502 | Phosphorylation | Uniprot |
研究背景
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.
Cytoplasm>Cytoskeleton.
Note: In elongating spermatid tail midpiece, localized in outer dense fibers (ODFs) and associates with mitochondria. Also localizes to the manchette in elongating spermatids.
Oligomer composed of two heavy chains and two light chains. Associates with microtubulin in an ATP-dependent manner. Interacts with KIF5C. Interacts with ODF1 (By similarity). Interacts with LRGUK (By similarity).
The heptad repeat (HR) motif is sufficient for interaction with kinesin heavy (KHL) chains and ODF1. The TPR region is involved in mitochondrial binding (By similarity).
Belongs to the kinesin light chain family.
研究領域
· Human Diseases > Infectious diseases: Bacterial > Salmonella infection.
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