製品: KLF13 Antibody
カタログ: DF13113
タンパク質の説明: Rabbit polyclonal antibody to KLF13
アプリケーション: WB IHC
反応性: Human, Rat
予測: Pig, Zebrafish, Bovine, Xenopus
分子量: 45 kDa; 31kD(Calculated).
ユニプロット: Q9Y2Y9
RRID: AB_2846073

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat
予測:
Pig(92%), Zebrafish(92%), Bovine(100%), Xenopus(100%)
クローナリティ:
Polyclonal
特異性:
KLF13 Antibody detects endogenous levels of total KLF13.
RRID:
AB_2846073
引用形式: Affinity Biosciences Cat# DF13113, RRID:AB_2846073.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Basic transcription element binding protein 3; Basic transcription element-binding protein 3; BTE binding protein 3; BTE-binding protein 3; BTEB3; C2 H2 zinc finger protein; FKLF 2; FKLF2; Klf13; KLF13_HUMAN; Krueppel-like factor 13; Kruppel like factor 13; Novel Sp1 like zinc finger transcription factor; Novel Sp1-like zinc finger transcription factor 1; NSLP1; RANTES factor of late activated T lymphocytes 1; RANTES factor of late activated T-lymphocytes 1; RFLAT 1; RFLAT-1; RFLAT1; Transcription factor BTEB3; Transcription factor NSLP1;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9Y2Y9 KLF13_HUMAN:

Ubiquitous.

タンパク質配列:
MAAAAYVDHFAAECLVSMSSRAVVHGPREGPESRPEGAAVAATPTLPRVEERRDGKDSASLFVVARILADLNQQAPAPAPAERREGAAARKARTPCRLPPPAPEPTSPGAEGAAAAPPSPAWSEPEPEAGLEPEREPGPAGSGEPGLRQRVRRGRSRADLESPQRKHKCHYAGCEKVYGKSSHLKAHLRTHTGERPFACSWQDCNKKFARSDELARHYRTHTGEKKFSCPICEKRFMRSDHLTKHARRHANFHPGMLQRRGGGSRTGSLSDYSRSDASSPTISPASSP

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Xenopus
100
Pig
92
Zebrafish
92
Horse
0
Sheep
0
Dog
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9Y2Y9 基板として

Site PTM Type Enzyme
T43 Phosphorylation
K56 Ubiquitination
S60 Phosphorylation
S119 Phosphorylation
S123 Phosphorylation
S162 Phosphorylation
K166 Acetylation
K168 Acetylation
K168 Ubiquitination
K176 Ubiquitination
K180 Acetylation
K180 Ubiquitination
K185 Sumoylation
K185 Ubiquitination
T192 Phosphorylation
K206 Ubiquitination
T220 Phosphorylation
T222 Phosphorylation
K225 Acetylation
K225 Ubiquitination
K226 Acetylation
K226 Ubiquitination
K234 Ubiquitination
K244 Ubiquitination
S268 Phosphorylation
S270 Phosphorylation
S279 Phosphorylation
T281 Phosphorylation
S283 Phosphorylation
S287 Phosphorylation

研究背景

機能:

Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells.

PTMs:

Phosphorylated.

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitous.

タンパク質ファミリー:

The Ala/Pro-rich domain may contain discrete activation and repression subdomains and also can mediate protein-protein interactions.

Belongs to the Sp1 C2H2-type zinc-finger protein family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.