製品: NME5 Antibody
カタログ: DF13188
タンパク質の説明: Rabbit polyclonal antibody to NME5
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit
分子量: 24 kDa; 24kD(Calculated).
ユニプロット: P56597
RRID: AB_2846148

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Zebrafish(88%), Bovine(100%), Horse(89%), Sheep(100%), Rabbit(100%)
クローナリティ:
Polyclonal
特異性:
NME5 Antibody detects endogenous levels of total NME5.
RRID:
AB_2846148
引用形式: Affinity Biosciences Cat# DF13188, RRID:AB_2846148.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Inhibitor of p53 induced apoptosis beta; Inhibitor of p53-induced apoptosis-beta; IPIA beta; IPIA-beta; NDK-H 5; NDK5_HUMAN; NDP kinase homolog 5; NM23 H5; nm23-H5; Nm23-M5; NM23H5; NME/NM23 family member 5; NME5; Non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase); Nonmetastatic cells 5, protein expressed in; Nonmetastatic protein 23, homolog 5; Nucleoside diphosphate kinase homolog 5; Radial spoke 23 homolog; RSPH23; Testis specific nm23 homolog; Testis-specific nm23 homolog;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P56597 NDK5_HUMAN:

Specifically expressed in testis germinal cells.

タンパク質配列:
MEISMPPPQIYVEKTLAIIKPDIVDKEEEIQDIILRSGFTIVQRRKLRLSPEQCSNFYVEKYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLGPNNSLVAKETHPDSLRAIYGTDDLRNALHGSNDFAAAEREIRFMFPEVIVEPIPIGQAAKDYLNLHIMPTLLEGLTELCKQKPADPLIWLADWLLKNNPNKPKLCHHPIVEEPY

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Rabbit
100
Horse
89
Zebrafish
88
Xenopus
67
Chicken
67
Dog
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P56597 基板として

Site PTM Type Enzyme
Y58 Phosphorylation

研究背景

機能:

Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity).

組織特異性:

Specifically expressed in testis germinal cells.

タンパク質ファミリー:

Belongs to the NDK family.

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