製品: FOXG1 Antibody
カタログ: DF13235
タンパク質の説明: Rabbit polyclonal antibody to FOXG1
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
予測: Pig, Horse, Sheep, Dog, Chicken, Xenopus
分子量: 52kDa; 52kD(Calculated).
ユニプロット: P55316
RRID: AB_2846254

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Horse(100%), Sheep(100%), Dog(100%), Chicken(100%), Xenopus(100%)
クローナリティ:
Polyclonal
特異性:
FOXG1 Antibody detects endogenous levels of total FOXG1.
RRID:
AB_2846254
引用形式: Affinity Biosciences Cat# DF13235, RRID:AB_2846254.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

BF-1; BF-2; BF1; BF2; Brain factor 1; Brain factor 2; FHKL; FKH2; FKHL1; FKHL2; FKHL3; FKHL4; Forkhead box protein G1; Forkhead box protein G1A; Forkhead box protein G1B; Forkhead box protein G1C; Forkhead like 1; Forkhead like 2; Forkhead like 3; Forkhead like 4; Forkhead-related protein FKHL1; Forkhead-related protein FKHL2; Forkhead-related protein FKHL3; FOXG1; FOXG1_HUMAN; FOXG1A; FOXG1B; FOXG1C; HBF 1; HBF G2; hBF-2; HBF2; HFK1; HFK2; HFK3; KHL2; Oncogene QIN; QIN;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P55316 FOXG1_HUMAN:

Expression is restricted to the neurons of the developing telencephalon.

タンパク質配列:
MLDMGDRKEVKMIPKSSFSINSLVPEAVQNDNHHASHGHHNSHHPQHHHHHHHHHHHPPPPAPQPPPPPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQLLLPPPPPPPPAAALDGAKADGLGGKGEPGGGPGELAPVGPDEKEKGAGAGGEEKKGAGEGGKDGEGGKEGEKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTSRAKLAFKRGARLTSTGLTFMDRAGSLYWPMSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQNSLGNNHSFSTANGLSVDRLVNGEIPYATHHLTAAALAASVPCGLSVPCSGTYSLNPCSVNLLAGQTSYFFPHVPHPSMTSQSSTSMSARAASSSTSPQAPSTLPCESLRPSLPSFTTGLSGGLSDYFTHQNQGSSSNPLIH

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Sheep
100
Dog
100
Xenopus
100
Chicken
100
Bovine
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P55316 基板として

Site PTM Type Enzyme
K11 Acetylation
S19 Phosphorylation P48729 (CSNK1A1)
Y186 Phosphorylation
S228 Phosphorylation
S234 Phosphorylation
Y246 Phosphorylation
Y254 Phosphorylation
S277 Phosphorylation
T278 Phosphorylation
T279 Phosphorylation P31749 (AKT1)
S280 Phosphorylation

研究背景

機能:

Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expression is restricted to the neurons of the developing telencephalon.

サブユニット構造:

Interacts with KDM5B.

研究領域

· Environmental Information Processing > Signal transduction > FoxO signaling pathway.   (View pathway)

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