Mannosidase II Antibody - #DF13260
(1)
(5)
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13260, RRID:AB_2846279.
折りたたみ／展開
3-1; 6-alpha-mannosidase; Alpha mannosidase 2; alpha Mannosidase II; Alpha-mannosidase 2; AMAN II; Golgi alpha mannosidase II; Golgi alpha-mannosidase II; Golgi integral membrane protein 7; GOLIM7; MA2A1_HUMAN; MAN II; Man2a1; MANA 2; MANA2; MANII; Mann II; Mannosidase alpha class 2A member 1; Mannosidase Two; Mannosidase, alpha type II; Mannosidase, alpha, II; Mannosyl oligosaccharide 1 3 1 6 alpha mannosidase; Mannosyl oligosaccharide 1,3 1,6 alpha mannosidase; Mannosyl-oligosaccharide 1;
免疫原
- Q16706 MA2A1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKLSRQFTVFGSAIFCVVIFSLYLMLDRGHLDYPRNPRREGSFPQGQLSMLQEKIDHLERLLAENNEIISNIRDSVINLSESVEDGPKSSQSNFSQGAGSHLLPSQLSLSVDTADCLFASQSGSHNSDVQMLDVYSLISFDNPDGGVWKQGFDITYESNEWDTEPLQVFVVPHSHNDPGWLKTFNDYFRDKTQYIFNNMVLKLKEDSRRKFIWSEISYLSKWWDIIDIQKKDAVKSLIENGQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLENNIGVKPRSGWAIDPFGHSPTMAYLLNRAGLSHMLIQRVHYAVKKHFALHKTLEFFWRQNWDLGSVTDILCHMMPFYSYDIPHTCGPDPKICCQFDFKRLPGGRFGCPWGVPPETIHPGNVQSRARMLLDQYRKKSKLFRTKVLLAPLGDDFRYCEYTEWDLQFKNYQQLFDYMNSQSKFKVKIQFGTLSDFFDALDKADETQRDKGQSMFPVLSGDFFTYADRDDHYWSGYFTSRPFYKRMDRIMESHLRAAEILYYFALRQAHKYKINKFLSSSLYTALTEARRNLGLFQHHDAITGTAKDWVVVDYGTRLFHSLMVLEKIIGNSAFLLILKDKLTYDSYSPDTFLEMDLKQKSQDSLPQKNIIRLSAEPRYLVVYNPLEQDRISLVSVYVSSPTVQVFSASGKPVEVQVSAVWDTANTISETAYEISFRAHIPPLGLKVYKILESASSNSHLADYVLYKNKVEDSGIFTIKNMINTEEGITLENSFVLLRFDQTGLMKQMMTKEDGKHHEVNVQFSWYGTTIKRDKSGAYLFLPDGNAKPYVYTTPPFVRVTHGRIYSEVTCFFDHVTHRVRLYHIQGIEGQSVEVSNIVDIRKVYNREIAMKISSDIKSQNRFYTDLNGYQIQPRMTLSKLPLQANVYPMTTMAYIQDAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQGIQDNKITANLFRILLEKRSAVNTEEEKKSVSYPSLLSHITSSLMNHPVIPMANKFSSPTLELQGEFSPLQSSLPCDIHLVNLRTIQSKVGNGHSNEAALILHRKGFDCRFSSKGTGLFCSTTQGKILVQKLLNKFIVESLTPSSLSLMHSPPGTQNISEINLSPMEISTFRIQLR
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q16706 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y33 | Phosphorylation | Uniprot | |
| S75 | Phosphorylation | Uniprot | |
| N78 | N-Glycosylation | Uniprot | |
| S80 | Phosphorylation | Uniprot | |
| S82 | Phosphorylation | Uniprot | |
| S105 | O-Glycosylation | Uniprot | |
| T192 | Phosphorylation | Uniprot | |
| Y194 | Phosphorylation | Uniprot | |
| Y218 | Phosphorylation | Uniprot | |
| S307 | Phosphorylation | Uniprot | |
| K373 | Ubiquitination | Uniprot | |
| Y407 | Phosphorylation | Uniprot | |
| Y442 | Phosphorylation | Uniprot | |
| K473 | Ubiquitination | Uniprot | |
| T509 | Phosphorylation | Uniprot | |
| Y514 | Phosphorylation | Uniprot | |
| Y532 | Phosphorylation | Uniprot | |
| Y533 | Phosphorylation | Uniprot | |
| K716 | Ubiquitination | Uniprot | |
| S723 | Phosphorylation | Uniprot | |
| Y733 | Phosphorylation | Uniprot | |
| K737 | Ubiquitination | Uniprot | |
| K739 | Ubiquitination | Uniprot | |
| S743 | Phosphorylation | Uniprot | |
| T747 | Phosphorylation | Uniprot | |
| K801 | Ubiquitination | Uniprot | |
| Y852 | Phosphorylation | Uniprot | |
| S865 | Phosphorylation | Uniprot | |
| K887 | Ubiquitination | Uniprot | |
| S998 | Phosphorylation | Uniprot | |
| N1125 | N-Glycosylation | Uniprot |
研究背景
Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
Glycosylated.
Golgi apparatus membrane>Single-pass type II membrane protein.
Homodimer; disulfide-linked.
Belongs to the glycosyl hydrolase 38 family.
研究領域
· Metabolism > Glycan biosynthesis and metabolism > N-Glycan biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
参考文献
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