CNGA2 Antibody - #DF13311
| 製品: | CNGA2 Antibody |
| カタログ: | DF13311 |
| タンパク質の説明: | Rabbit polyclonal antibody to CNGA2 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Horse, Sheep, Rabbit, Dog |
| 分子量: | 76kDa; 76kD(Calculated). |
| ユニプロット: | Q16280 |
| RRID: | AB_2846330 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13311, RRID:AB_2846330.
折りたたみ／展開
CNCA; CNCA1; CNCG2; CNG 2; CNG channel alpha 2; CNG channel alpha-2; CNG-2; CNG2; CNGA 2; Cnga2; CNGA2_HUMAN; Cyclic nucleotide gated cation channel 2; Cyclic nucleotide gated channel alpha 2; Cyclic nucleotide gated olfactory channel; Cyclic nucleotide-gated cation channel 2; Cyclic nucleotide-gated channel alpha-2; Cyclic nucleotide-gated olfactory channel; FLJ46312; OCNC1; OCNCa; OCNCALPHA;
免疫原
A synthesized peptide derived from human CNGA2, corresponding to a region within C-terminal amino acids.
- Q16280 CNGA2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTEKTNGVKSSPANNHNHHAPPAIKANGKDDHRTSSRPHSAADDDTSSELQRLADVDAPQQGRSGFRRIVRLVGIIREWANKNFREEEPRPDSFLERFRGPELQTVTTQEGDGKGDKDGEDKGTKKKFELFVLDPAGDWYYCWLFVIAMPVLYNWCLLVARACFSDLQKGYYLVWLVLDYVSDVVYIADLFIRLRTGFLEQGLLVKDTKKLRDNYIHTLQFKLDVASIIPTDLIYFAVDIHSPEVRFNRLLHFARMFEFFDRTETRTNYPNIFRISNLVLYILVIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKGMEAKVIRWFDYLWTNKKTVDEREILKNLPAKLRAEIAINVHLSTLKKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDENEVATSMEVDVQEKLGQLETNMETLYTRFGRLLAEYTGAQQKLKQRITVLETKMKQNNEDDYLSDGMNSPELAAADEP
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q16280 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y395 | Phosphorylation | Uniprot | |
| T422 | Phosphorylation | Uniprot | |
| Y492 | Phosphorylation | Uniprot | |
| S546 | Phosphorylation | Uniprot | |
| S552 | Phosphorylation | Uniprot | |
| Y563 | Phosphorylation | Uniprot | |
| T634 | Phosphorylation | Uniprot |
研究背景
Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.
Membrane>Multi-pass membrane protein.
Heterotetramer composed of two subunits of CNGA2, one of CNGA4 and one of CNGB1b. The complex forms the cyclic nucleotide-gated (CNG) channel of olfactory sensory neurons (By similarity).
The C-terminal coiled-coil domain mediates trimerization of CNGA subunits.
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA2 subfamily.
研究領域
· Environmental Information Processing > Signal transduction > cAMP signaling pathway. (View pathway)
· Organismal Systems > Sensory system > Olfactory transduction.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.