製品: Syntaxin 2 Antibody
カタログ: DF13316
タンパク質の説明: Rabbit polyclonal antibody to Syntaxin 2
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
予測: Pig, Horse, Sheep, Rabbit, Dog
分子量: 33kDa; 33kD(Calculated).
ユニプロット: P32856
RRID: AB_2846335

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
Syntaxin 2 Antibody detects endogenous levels of total Syntaxin 2.
RRID:
AB_2846335
引用形式: Affinity Biosciences Cat# DF13316, RRID:AB_2846335.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

EPIM; Epimorphin; EPM; MGC51014; OTTHUMP00000238636; OTTHUMP00000238637; Stx2; STX2_HUMAN; STX2A; STX2B; STX2C; Syntaxin 2A; Syntaxin 2B; Syntaxin 2C; Syntaxin-2;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGLSVGK

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Sheep
100
Dog
100
Rabbit
100
Chicken
60
Bovine
0
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P32856 基板として

Site PTM Type Enzyme
Y49 Phosphorylation
K55 Methylation
K55 Ubiquitination
K69 Ubiquitination
K71 Methylation
K87 Acetylation
K91 Acetylation
K93 Acetylation
K93 Ubiquitination
K125 Methylation
K199 Acetylation

研究背景

機能:

Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.

細胞の位置付け:

Membrane>Single-pass type IV membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with SYT6 and SYT8; the interaction is Ca(2+)-dependent.

タンパク質ファミリー:

Belongs to the syntaxin family.

研究領域

· Genetic Information Processing > Folding, sorting and degradation > SNARE interactions in vesicular transport.

· Organismal Systems > Nervous system > Synaptic vesicle cycle.

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