ERp29 Antibody - #DF13338
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13338, RRID:AB_2846357.
折りたたみ／展開
C12orf8; Chromosome 12 open reading frame 8; Endoplasmic reticulum lumenal protein ERp28; Endoplasmic reticulum protein 29; Endoplasmic reticulum protein 29 isoform 1; Endoplasmic reticulum protein ERp29; Endoplasmic reticulum resident protein 28; Endoplasmic reticulum resident protein 29; Endoplasmic reticulum resident protein 31; Epididymis secretory protein Li 107; ERp28; ERP29_HUMAN; ERp31; HEL S 107; PDI-DB; PDIA9; Protein disulfide isomerase family A member 9;
免疫原
- P30040 ERP29_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAAVPRAAFLSPLLPLLLGFLLLSAPHGGSGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSDDLLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFRDGDFENPVPYTGAVKVGAIQRWLKGQGVYLGMPGCLPVYDALAGEFIRASGVEARQALLKQGQDNLSSVKETQKKWAEQYLKIMGKILDQGEDFPASEMTRIARLIEKNKMSDGKKEELQKSLNILTAFQKKGAEKEEL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P30040 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y47 | Phosphorylation | Uniprot | |
| K48 | Ubiquitination | Uniprot | |
| Y64 | Phosphorylation | Uniprot | |
| Y66 | Phosphorylation | Uniprot | |
| K69 | Ubiquitination | Uniprot | |
| S80 | Phosphorylation | Uniprot | |
| S83 | Phosphorylation | Uniprot | |
| Y119 | Phosphorylation | Uniprot | |
| R122 | Methylation | Uniprot | |
| T133 | Phosphorylation | Uniprot | |
| K137 | Ubiquitination | Uniprot | |
| K182 | Ubiquitination | Uniprot | |
| K192 | Ubiquitination | Uniprot | |
| T222 | Phosphorylation | Uniprot | |
| K243 | Ubiquitination | Uniprot | |
| S244 | Phosphorylation | Uniprot | |
| T249 | Phosphorylation | Uniprot |
研究背景
Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER.
Endoplasmic reticulum lumen. Melanosome.
Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Ubiquitous. Mostly expressed in secretory tissues.
Homodimer. Part of a large chaperone multiprotein complex comprising CABP1, DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX.
研究領域
· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum. (View pathway)
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