CD1a Antibody - #DF13391
(2)
(4)
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13391, RRID:AB_2846410.
折りたたみ／展開
CD 1a; CD1; CD1a; CD1A Antigen; CD1A antigen, a polypeptide; CD1a molecule; CD1A_HUMAN; cluster of differentiation 1 A; cortical thymocyte antigen CD1A; differentiation antigen CD1 alpha 3; epidermal dendritic cell marker CD1a; FCB 6; FCB6; HTA 1; HTA1; hTa1 thymocyte antigen; OTTHUMP00000018907; R 4; R4; T 6; T-cell surface antigen T6/Leu-6; T-cell surface glycoprotein CD1a; T6;
免疫原
Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues.
- P06126 CD1A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSNSSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSVGFIILAVIVPLLLLIGLALWFRKRCFC
PTMs - P06126 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N37 | N-Glycosylation | Uniprot | |
| N74 | N-Glycosylation | Uniprot | |
| K81 | Ubiquitination | Uniprot | |
| N145 | N-Glycosylation | Uniprot | |
| K163 | Ubiquitination | Uniprot | |
| K195 | Ubiquitination | Uniprot |
研究背景
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Cell membrane>Single-pass type I membrane protein. Membrane raft>Single-pass type I membrane protein. Endosome membrane>Single-pass type I membrane protein.
Note: Subject to intracellular trafficking between the cell membrane and endosomes (PubMed:11231314). Localizes to cell surface lipid rafts (PubMed:18178838).
Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues.
Heterodimer with B2M (beta-2-microglobulin). Interacts with CD74.
研究領域
· Cellular Processes > Cellular community - eukaryotes > Tight junction. (View pathway)
· Organismal Systems > Immune system > Hematopoietic cell lineage. (View pathway)
参考文献
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