Surfactant Protein A Antibody - #DF13404

(4)  
製品: Surfactant Protein A Antibody
カタログ: DF13404
タンパク質の説明: Rabbit polyclonal antibody to Surfactant Protein A
アプリケーション: WB IHC IF/ICC
反応性: Human
分子量: 26kDa; 26kD(Calculated).
ユニプロット: Q8IWL1
RRID: AB_2846423

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500, WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
Surfactant Protein A Antibody detects endogenous levels of total Surfactant Protein A.
RRID:
AB_2846423
引用形式: Affinity Biosciences Cat# DF13404, RRID:AB_2846423.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

免疫原

免疫原:
Uniprot:

Q8IWL1(SFPA2_HUMAN) >>Visit HPA database.

遺伝子(ID):
SFTPA2(729238)
タンパク質配列:
MWLCPLALNLILMAASGAACEVKDVCVGSPGIPGTPGSHGLPGRDGRDGVKGDPGPPGPMGPPGETPCPPGNNGLPGAPGVPGERGEKGEAGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF

PTMs - Q8IWL1 基板として

Site PTM Type Enzyme
Y184 Phosphorylation
S241 Phosphorylation

研究背景

機能:

In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.

PTMs:

N-acetylated.

細胞の位置付け:

Secreted>Extracellular space>Extracellular matrix. Secreted>Extracellular space>Surface film.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Oligomeric complex of 6 set of homotrimers.

タンパク質ファミリー:

Belongs to the SFTPA family.

研究領域

· Cellular Processes > Transport and catabolism > Phagosome.   (View pathway)

· Human Diseases > Infectious diseases: Bacterial > Pertussis.

Restrictive clause

 

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For Research Use Only.
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