Natriuretic Peptide Receptor C Antibody - #DF13434
| 製品: | Natriuretic Peptide Receptor C Antibody |
| カタログ: | DF13434 |
| タンパク質の説明: | Rabbit polyclonal antibody to Natriuretic Peptide Receptor C |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 59kDa; 60kD(Calculated). |
| ユニプロット: | P17342 |
| RRID: | AB_2846453 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13434, RRID:AB_2846453.
折りたたみ／展開
ANP C; ANP-C; ANPC; ANPR-C; ANPRC; ANPRC_HUMAN; Atrial natriuretic peptide C type receptor; Atrial natriuretic peptide clearance receptor; Atrial natriuretic peptide receptor 3; Atrial natriuretic peptide receptor type C; Atrionatriuretic peptide receptor C; C5orf23; FLJ14054; GUCY2B; MGC22189; Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C); Natriuretic peptide receptor C/guanylate cyclase C; NPR 3; NPR C; NPR-C; Npr3; NPRC;
免疫原
- P17342 ANPRC_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLPQDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSSGGLEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHRELREDSIRSHFSVA
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P17342 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N86 | N-Glycosylation | Uniprot | |
| S148 | Phosphorylation | Uniprot | |
| S156 | Phosphorylation | Uniprot | |
| N293 | N-Glycosylation | Uniprot | |
| Y316 | Phosphorylation | Uniprot | |
| N394 | N-Glycosylation | Uniprot | |
| Y502 | Phosphorylation | Uniprot | |
| K525 | Ubiquitination | Uniprot | |
| S533 | Phosphorylation | Uniprot |
研究背景
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
Membrane>Single-pass type I membrane protein.
Homodimer; disulfide-linked. Dimers can also be formed through the C-terminal cysteine of isoform 2. Interacts with OSTN (By similarity).
Belongs to the ANF receptor family.
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