TECK Antibody - #DF13462
| 製品: | TECK Antibody |
| カタログ: | DF13462 |
| タンパク質の説明: | Rabbit polyclonal antibody to TECK |
| アプリケーション: | WB |
| 反応性: | Human |
| 分子量: | 16kDa; 17kD(Calculated). |
| ユニプロット: | O15444 |
| RRID: | AB_2846481 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13462, RRID:AB_2846481.
折りたたみ／展開
A130072A22Rik; C-C motif chemokine 25; CCL 25; CCL25; CCL25_HUMAN; Chemokine (C C motif) ligand 25; Chemokine (CC motif) ligand 25; Chemokine C C motif ligand 25; Chemokine CC motif ligand 25; Chemokine TECK; Ck beta 15; Ckb 15; Ckb15; MGC125074; MGC150327; SCY A25; SCYA 25; SCYA25; Small inducible cytokine A25; Small inducible cytokine A25 isoform 1 precursor; Small inducible cytokine A25 isoform 2 precursor; Small inducible cytokine subfamily A (Cys Cys) member 25; Small inducible cytokine subfamily A Cys Cys member 25; Small inducible cytokine subfamily A, member 25; Small-inducible cytokine A25; TECK; TECKvar; Thymus expressed chemokine; Thymus-expressed chemokine;
免疫原
Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine.
- O15444 CCL25_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNLWLLACLVAGFLGAWAPAVHTQGVFEDCCLAYHYPIGWAVLRRAWTYRIQEVSGSCNLPAAIFYLPKRHRKVCGNPKSREVQRAMKLLDARNKVFAKLHHNTQTFQAGPHAVKKLSSGNSKLSSSKFSNPISSSKRNVSLLISANSGL
PTMs - O15444 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T104 | Phosphorylation | Uniprot | |
| S135 | Phosphorylation | Uniprot | |
| S141 | Phosphorylation | Uniprot |
研究背景
Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Secreted.
Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine.
Belongs to the intercrine beta (chemokine CC) family.
研究領域
· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction. (View pathway)
· Organismal Systems > Immune system > Chemokine signaling pathway. (View pathway)
· Organismal Systems > Immune system > Intestinal immune network for IgA production. (View pathway)
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