製品: Fumarylacetoacetate hydrolase Antibody
カタログ: DF13497
タンパク質の説明: Rabbit polyclonal antibody to Fumarylacetoacetate hydrolase
アプリケーション: WB
反応性: Human, Mouse, Rat
予測: Bovine
分子量: 46kDa; 46kD(Calculated).
ユニプロット: P16930
RRID: AB_2846516

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Bovine(88%)
クローナリティ:
Polyclonal
特異性:
Fumarylacetoacetate hydrolase Antibody detects endogenous levels of total Fumarylacetoacetate hydrolase.
RRID:
AB_2846516
引用形式: Affinity Biosciences Cat# DF13497, RRID:AB_2846516.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Beta diketonase; FAA; FAH; Fumarylacetoacetase; Fumarylacetoacetate; Fumarylacetoacetate hydrolase;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P16930 FAAA_HUMAN:

Mainly expressed in liver and kidney. Lower levels are also detected in many other tissues.

タンパク質配列:
MSFIPVAEDSDFPIHNLPYGVFSTRGDPRPRIGVAIGDQILDLSIIKHLFTGPVLSKHQDVFNQPTLNSFMGLGQAAWKEARVFLQNLLSVSQARLRDDTELRKCAFISQASATMHLPATIGDYTDFYSSRQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMKPDDSKPPVYGACKLLDMELEMAFFVGPGNRLGEPIPISKAHEHIFGMVLMNDWSARDIQKWEYVPLGPFLGKSFGTTVSPWVVPMDALMPFAVPNPKQDPRPLPYLCHDEPYTFDINLSVNLKGEGMSQAATICKSNFKYMYWTMLQQLTHHSVNGCNLRPGDLLASGTISGPEPENFGSMLELSWKGTKPIDLGNGQTRKFLLDGDEVIITGYCQGDGYRIGFGQCAGKVLPALLPS

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
88
Chicken
71
Horse
50
Pig
0
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P16930 基板として

Site PTM Type Enzyme
S2 Acetylation
K79 Acetylation
Y128 Phosphorylation
K144 Ubiquitination
S219 Phosphorylation
K241 Acetylation
K241 Ubiquitination
Y244 Phosphorylation
S309 Phosphorylation
T313 Phosphorylation
T370 Phosphorylation
K371 Ubiquitination
Y395 Phosphorylation
K411 Ubiquitination
S419 Phosphorylation

研究背景

組織特異性:

Mainly expressed in liver and kidney. Lower levels are also detected in many other tissues.

サブユニット構造:

Homodimer.

タンパク質ファミリー:

Belongs to the FAH family.

研究領域

· Metabolism > Amino acid metabolism > Tyrosine metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

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