製品: KCNK9 Antibody
カタログ: DF13498
タンパク質の説明: Rabbit polyclonal antibody to KCNK9
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Rabbit, Chicken, Xenopus
分子量: 42kDa; 42kD(Calculated).
ユニプロット: Q9NPC2
RRID: AB_2846517

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Horse(100%), Rabbit(100%), Chicken(83%), Xenopus(83%)
クローナリティ:
Polyclonal
特異性:
KCNK9 Antibody detects endogenous levels of total KCNK9.
RRID:
AB_2846517
引用形式: Affinity Biosciences Cat# DF13498, RRID:AB_2846517.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Acid sensitive potassium channel protein TASK 3; K2p9.1; KT3.2; MGC138268; MGC138270; Potassium channel TASK3; Potassium channel, subfamily K, member 9 (TASK 3); Potassium channel, subfamily K, member 9; TASK 3; TWIK related acid sensitive K+ channel 3;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9NPC2 KCNK9_HUMAN:

Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung.

タンパク質配列:
MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPRYKADVPDLQSVCSCTCYRSQDYGGRSVAPQNSFSAKLAPHYFHSISYKIEEISPSTLKNSLFPSPISSISPGLHSFTDHQRLMKRRKSV

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Rabbit
100
Xenopus
83
Chicken
83
Sheep
0
Dog
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NPC2 基板として

Site PTM Type Enzyme
S56 Phosphorylation
Y59 Phosphorylation
Y113 Phosphorylation
Y138 Phosphorylation
K144 Acetylation
Y286 Phosphorylation
T341 Phosphorylation
S349 Phosphorylation
S352 Phosphorylation
S353 Phosphorylation
S373 Phosphorylation P17612 (PRKACA)

研究背景

機能:

pH-dependent, voltage-insensitive, background potassium channel protein.

細胞の位置付け:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung.

サブユニット構造:

Homodimer (Probable). Heterodimer with KCNK1.

タンパク質ファミリー:

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

研究領域

· Organismal Systems > Endocrine system > Aldosterone synthesis and secretion.

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