Ornithine Carbamoyltransferase Antibody - #DF13552
| 製品: | Ornithine Carbamoyltransferase Antibody |
| カタログ: | DF13552 |
| タンパク質の説明: | Rabbit polyclonal antibody to Ornithine Carbamoyltransferase |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 39kDa, 55 kDa; 40kD(Calculated). |
| ユニプロット: | P00480 |
| RRID: | AB_2846571 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13552, RRID:AB_2846571.
折りたたみ／展開
EC 2.1.3.3; MGC129967; MGC129968; MGC138856; OCTD; Ornithine Carbamoyltransferase; Ornithine carbamoyltransferase mitochondrial; Ornithine carbamoyltransferase, mitochondrial; Ornithine transcarbamylase; Otc; OTC_HUMAN; OTCase;
免疫原
- P00480 OTC_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLFNLRILLNNAAFRNGHNFMVRNFRCGQPLQNKVQLKGRDLLTLKNFTGEEIKYMLWLSADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWIGDGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKKKRLQAFQGYQVTMKTAKVAASDWTFLHCLPRKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLLTDYSPQLQKPKF
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P00480 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K46 | Acetylation | Uniprot | |
| Y55 | Phosphorylation | Uniprot | |
| K88 | Acetylation | Uniprot | |
| S133 | Phosphorylation | Uniprot | |
| S146 | Phosphorylation | Uniprot | |
| Y223 | Phosphorylation | Uniprot | |
| K231 | Acetylation | Uniprot | |
| Y284 | Phosphorylation | Uniprot | |
| Y317 | Phosphorylation | Uniprot |
研究背景
Acetylation at Lys-88 negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals.
Mitochondrion matrix.
Mainly expressed in liver and intestinal mucosa.
Homotrimer.
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
研究領域
· Metabolism > Amino acid metabolism > Arginine biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > Biosynthesis of amino acids.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.