ALDH9A1 Antibody - #DF13562
| 製品: | ALDH9A1 Antibody |
| カタログ: | DF13562 |
| タンパク質の説明: | Rabbit polyclonal antibody to ALDH9A1 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 53kDa; 54kD(Calculated). |
| ユニプロット: | P49189 |
| RRID: | AB_2846581 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13562, RRID:AB_2846581.
折りたたみ／展開
4 trimethylaminobutyraldehyde dehydrogenase; 4-trimethylaminobutyraldehyde dehydrogenase; AL9A1_HUMAN; aldehyde dehydrogenase (NAD+); Aldehyde dehydrogenase 9A1; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; ALDH4; ALDH7; ALDH9; aldh9A1; E3; Gamma aminobutyraldehyde dehydrogenase; Gamma-aminobutyraldehyde dehydrogenase; R aminobutyraldehyde dehydrogenase; R-aminobutyraldehyde dehydrogenase; TMABADH;
免疫原
Detected in brain (at protein level) (PubMed:8645224). High expression in adult liver, skeletal muscle, and kidney. Low levels in heart, pancreas, lung and brain (PubMed:8786138). Expressed in all regions of the brain. Expression levels are variable in the different brain areas, with the highest levels in the spinal cord and the lowest in the occipital pole.
- P49189 AL9A1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSTGTFVVSQPLNYRGGARVEPADASGTEKAFEPATGRVIATFTCSGEKEVNLAVQNAKAAFKIWSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPGLFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVESAF
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P49189 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S9 | Phosphorylation | Uniprot | |
| R15 | Methylation | Uniprot | |
| K30 | Acetylation | Uniprot | |
| K30 | Ubiquitination | Uniprot | |
| K49 | Ubiquitination | Uniprot | |
| K59 | Ubiquitination | Uniprot | |
| K68 | Ubiquitination | Uniprot | |
| S233 | Phosphorylation | Uniprot | |
| K239 | Ubiquitination | Uniprot | |
| K246 | Ubiquitination | Uniprot | |
| K249 | Ubiquitination | Uniprot | |
| K258 | Ubiquitination | Uniprot | |
| K298 | Acetylation | Uniprot | |
| K298 | Ubiquitination | Uniprot | |
| K303 | Acetylation | Uniprot | |
| K303 | Ubiquitination | Uniprot | |
| K310 | Ubiquitination | Uniprot | |
| K316 | Ubiquitination | Uniprot | |
| K344 | Ubiquitination | Uniprot | |
| K347 | Ubiquitination | Uniprot | |
| K352 | Ubiquitination | Uniprot | |
| Y360 | Phosphorylation | Uniprot | |
| K366 | Ubiquitination | Uniprot | |
| K461 | Acetylation | Uniprot | |
| K462 | Acetylation | Uniprot | |
| Y476 | Phosphorylation | Uniprot |
研究背景
Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency.
Cytoplasm>Cytosol.
Detected in brain (at protein level). High expression in adult liver, skeletal muscle, and kidney. Low levels in heart, pancreas, lung and brain. Expressed in all regions of the brain. Expression levels are variable in the different brain areas, with the highest levels in the spinal cord and the lowest in the occipital pole.
Homotetramer.
Belongs to the aldehyde dehydrogenase family.
研究領域
· Metabolism > Carbohydrate metabolism > Glycolysis / Gluconeogenesis.
· Metabolism > Carbohydrate metabolism > Ascorbate and aldarate metabolism.
· Metabolism > Lipid metabolism > Fatty acid degradation.
· Metabolism > Amino acid metabolism > Valine, leucine and isoleucine degradation.
· Metabolism > Amino acid metabolism > Lysine degradation.
· Metabolism > Amino acid metabolism > Arginine and proline metabolism.
· Metabolism > Amino acid metabolism > Histidine metabolism.
· Metabolism > Amino acid metabolism > Tryptophan metabolism.
· Metabolism > Metabolism of other amino acids > beta-Alanine metabolism.
· Metabolism > Lipid metabolism > Glycerolipid metabolism.
· Metabolism > Carbohydrate metabolism > Pyruvate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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