製品: TROY Antibody
カタログ: DF13610
タンパク質の説明: Rabbit polyclonal antibody to TROY
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Horse, Sheep
分子量: 46kDa; 46kD(Calculated).
ユニプロット: Q9NS68
RRID: AB_2846629

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Horse(88%), Sheep(86%)
クローナリティ:
Polyclonal
特異性:
TROY Antibody detects endogenous levels of total TROY.
RRID:
AB_2846629
引用形式: Affinity Biosciences Cat# DF13610, RRID:AB_2846629.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

AL023044; AW123854; TAJ alpha; TAJ; TAJ-alpha; TNFRSF19; TNFRSF19 tumor necrosis factor receptor superfamily, member 19; TNR19_HUMAN; Toxicity and JNK inducer; TRADE; TROY; Tumor necrosis factor receptor superfamily member 19; UNQ1888/PRO4333;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9NS68 TNR19_HUMAN:

Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes.

タンパク質配列:
MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANCSATSDAICGDCLPGFYRKTKLVGFQDMECVPCGDPPPPYEPHCASKVNLVKIASTASSPRDTALAAVICSALATVLLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSELSCFDRPQLHEYAHRACCQCRRDSVQTCGPVRLLPSMCCEEACSPNPATLGCGVHSAASLQARNAGPAGEMVPTFFGSLTQSICGEFSDAWPLMQNPMGGDNISFCDSYPELTGEDIHSLNPELESSTSLDSNSSQDLVGGAVPVQSHSENFTAATDLSRYNNTLVESASTQDALTMRSQLDQESGAVIHPATQTSLQVRQRLGSL

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
88
Sheep
86
Pig
75
Dog
75
Rabbit
75
Bovine
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NS68 基板として

Site PTM Type Enzyme
S110 Phosphorylation
Y122 Phosphorylation
T125 Phosphorylation
S216 Phosphorylation
S241 Phosphorylation
T244 Phosphorylation
S261 Phosphorylation

研究背景

機能:

Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.

細胞の位置付け:

Membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes.

サブユニット構造:

Associates with TRAF1, TRAF2, TRAF3 and TRAF5. Interacts with LINGO1.

研究領域

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

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