製品: Gastrin Releasing Peptide Antibody
カタログ: DF13618
タンパク質の説明: Rabbit polyclonal antibody to Gastrin Releasing Peptide
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Horse, Rabbit
分子量: 16kDa; 16kD(Calculated).
ユニプロット: P07492
RRID: AB_2846637

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Horse(86%), Rabbit(100%)
クローナリティ:
Polyclonal
特異性:
Gastrin Releasing Peptide Antibody detects endogenous levels of total Gastrin Releasing Peptide.
RRID:
AB_2846637
引用形式: Affinity Biosciences Cat# DF13618, RRID:AB_2846637.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

BN; Gastric releasing peptide; Gastrin releasing peptide; GRP 10; GRP; GRP10; Neuromedin C; NeuromedinC; Pre progastrin releasing peptide; PreproGRP; ProGRP;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSSVSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFKDVGSKGKVGRLSAPGSQREGRNPQLNQQ

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Horse
86
Xenopus
71
Pig
0
Bovine
0
Sheep
0
Dog
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P07492 基板として

Site PTM Type Enzyme
T32 Phosphorylation
K52 Ubiquitination
K53 Ubiquitination
K68 Acetylation
K127 Acetylation

研究背景

機能:

Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity).

細胞の位置付け:

Secreted. Cytoplasmic vesicle>Secretory vesicle lumen.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the bombesin/neuromedin-B/ranatensin family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.