製品: ESD Antibody
カタログ: DF13683
タンパク質の説明: Rabbit polyclonal antibody to ESD
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
予測: Pig, Horse, Rabbit, Dog
分子量: 31kDa, 40 kDa; 31kD(Calculated).
ユニプロット: P10768
RRID: AB_2846702

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Horse(100%), Rabbit(88%), Dog(88%)
クローナリティ:
Polyclonal
特異性:
ESD Antibody detects endogenous levels of total ESD.
RRID:
AB_2846702
引用形式: Affinity Biosciences Cat# DF13683, RRID:AB_2846702.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

EC 3.1.2.12; Es-10; Es10; ESD; ESTD_HUMAN; Esterase 10; Esterase D; Esterase D formylglutathione hydrolase; FGH; FGH, included; FLJ11763; Methylumbelliferyl acetate deacetylase; MGC139609; OTTHUMP00000018374; OTTHUMP00000040929; S formylglutathione hydrolase; S-formylglutathione hydrolase; S-formylglutathione hydrolase, included; Sid 478; sid478;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MALKQISSNKCFGGLQKVFEHDSVELNCKMKFAVYLPPKAETGKCPALYWLSGLTCTEQNFISKSGYHQSASEHGLVVIAPDTSPRGCNIKGEDESWDFGTGAGFYVDATEDPWKTNYRMYSYVTEELPQLINANFPVDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPICNPVLCPWGKKAFSGYLGTDQSKWKAYDATHLVKSYPGSQLDILIDQGKDDQFLLDGQLLPDNFIAACTEKKIPVVFRLQEGYDHSYYFIATFITDHIRHHAKYLNA

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Dog
88
Rabbit
88
Bovine
75
Sheep
75
Xenopus
75
Zebrafish
75
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P10768 基板として

Site PTM Type Enzyme
K4 Acetylation
K4 Ubiquitination
K10 Acetylation
K10 Ubiquitination
C11 S-Nitrosylation
K17 Ubiquitination
C28 S-Nitrosylation
K29 Ubiquitination
K31 Ubiquitination
K39 Acetylation
K39 Ubiquitination
S144 Phosphorylation
S149 Phosphorylation
K167 Ubiquitination
S170 Phosphorylation
C176 S-Nitrosylation
C181 S-Nitrosylation
K185 Acetylation
K185 Ubiquitination
K186 Acetylation
K186 Ubiquitination
S197 Phosphorylation
K198 Ubiquitination
K200 Acetylation
K200 Ubiquitination
Y202 Phosphorylation
K209 Ubiquitination
S214 Phosphorylation
K246 Ubiquitination
K247 Ubiquitination
Y258 Phosphorylation
Y262 Phosphorylation
Y263 Phosphorylation
K278 Acetylation

研究背景

機能:

Serine hydrolase involved in the detoxification of formaldehyde.

細胞の位置付け:

Cytoplasm. Cytoplasmic vesicle.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Homodimer.

タンパク質ファミリー:

Belongs to the esterase D family.

研究領域

· Metabolism > Global and overview maps > Carbon metabolism.

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For Research Use Only.
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