TBKBP1 Antibody - #DF13686
| 製品: | TBKBP1 Antibody |
| カタログ: | DF13686 |
| タンパク質の説明: | Rabbit polyclonal antibody to TBKBP1 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 67kDa; 68kD(Calculated). |
| ユニプロット: | A7MCY6 |
| RRID: | AB_2846705 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13686, RRID:AB_2846705.
折りたたみ／展開
KIAA0775; ProSAPiP2; SINTBAD; TANK binding kinase 1 binding protein 1; TANK-binding kinase 1-binding protein 1; TBK1 binding protein 1; TBK1-binding protein 1; TBKB1_HUMAN; Tbkbp1;
免疫原
Detected in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, muscle, heart, brain and at low levels in thymus.
- A7MCY6 TBKB1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MESMFEDDISILTQEALGPSEVWLDSPGDPSLGGDMCSASHFALITAYGDIKERLGGLERENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQKNKEQEEQLGEMIQAYEKLCVEKSDLETELREMRALVETHLRQICGLEQQLRQQQGLQDAAFSNLSPPPAPAPPCTDLDLHYLALRGGSGLSHAGWPGSTPSVSDLERRRLEEALEAAQGEARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGFPIPESPAATAYAHAEHAQSWPSINLLMETVGSDIRSCPLCQLGFPVGYPDDALIKHIDSHLENSKI
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - A7MCY6 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S10 | Phosphorylation | Uniprot | |
| T13 | Phosphorylation | Uniprot | |
| Y48 | Phosphorylation | Uniprot | |
| K70 | Ubiquitination | Uniprot | |
| S97 | Phosphorylation | Uniprot | |
| K103 | Ubiquitination | Uniprot | |
| S105 | Phosphorylation | Uniprot | |
| K119 | Ubiquitination | Uniprot | |
| K121 | Ubiquitination | Uniprot | |
| S184 | Phosphorylation | Uniprot | |
| K262 | Ubiquitination | Uniprot | |
| K285 | Ubiquitination | Uniprot | |
| S335 | Phosphorylation | Uniprot | |
| S349 | Phosphorylation | Uniprot | |
| S351 | Phosphorylation | Uniprot | |
| S365 | Phosphorylation | Uniprot | |
| S372 | Phosphorylation | Uniprot | |
| S379 | Phosphorylation | Uniprot | |
| S385 | Phosphorylation | Uniprot | |
| S388 | Phosphorylation | Uniprot | |
| S390 | Phosphorylation | Uniprot | |
| S393 | Phosphorylation | Uniprot | |
| S400 | Phosphorylation | Uniprot | |
| S405 | Phosphorylation | Uniprot | |
| S415 | Phosphorylation | Uniprot | |
| T485 | Phosphorylation | Uniprot | |
| S504 | Phosphorylation | Uniprot | |
| R513 | Methylation | Uniprot | |
| S521 | Phosphorylation | Uniprot | |
| S534 | Phosphorylation | Uniprot |
研究背景
Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity.
Detected in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, muscle, heart, brain and at low levels in thymus.
Homodimer. May form a heterodimer with NAP1. Interacts with TKB1 and IKBKE.
(Microbial infection) Interacts with vaccinia virus protein C6.
研究領域
· Organismal Systems > Immune system > RIG-I-like receptor signaling pathway. (View pathway)
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.