TCP1 beta Antibody - #DF13690
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13690, RRID:AB_2846709.
折りたたみ／展開
99D8.1; CCT 2; CCT beta; CCT-beta; CCT2; CCTB; Chaperonin containing t complex polypeptide 1 beta subunit; Chaperonin containing t complex polypeptide 1 subunit 2; Chaperonin containing TCP1 subunit 2; Chaperonin containing TCP1 subunit 2 (beta); CTP:phosphocholine cytidylyltransferase 2; Epididymis secretory sperm binding protein Li 100n; HEL S 100n; MGC142074; MGC142076; MGC94480; PRO1633; T complex protein 1 beta subunit; T complex protein 1 subunit beta; T-complex protein 1 subunit beta; TCP 1 beta; TCP-1-beta; TCPB_HUMAN;
免疫原
- P78371 TCPB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P78371 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| S3 | Phosphorylation | Uniprot | |
| S5 | Phosphorylation | Uniprot | |
| K13 | Acetylation | Uniprot | |
| K13 | Ubiquitination | Uniprot | |
| T23 | Phosphorylation | Uniprot | |
| S28 | Phosphorylation | Uniprot | |
| K40 | Ubiquitination | Uniprot | |
| K46 | Ubiquitination | Uniprot | |
| K50 | Ubiquitination | Uniprot | |
| S54 | Phosphorylation | Uniprot | |
| S55 | Phosphorylation | Uniprot | |
| S60 | Phosphorylation | Uniprot | |
| K72 | Ubiquitination | Uniprot | |
| K82 | Ubiquitination | Uniprot | |
| S115 | Phosphorylation | Uniprot | |
| K119 | Ubiquitination | Uniprot | |
| K120 | Ubiquitination | Uniprot | |
| S143 | Phosphorylation | Uniprot | |
| S150 | Phosphorylation | Uniprot | |
| K154 | Acetylation | Uniprot | |
| K154 | Ubiquitination | Uniprot | |
| T165 | Phosphorylation | Uniprot | |
| T166 | Phosphorylation | Uniprot | |
| S168 | Phosphorylation | Uniprot | |
| S169 | Phosphorylation | Uniprot | |
| K170 | Ubiquitination | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| K181 | Acetylation | Uniprot | |
| K191 | Acetylation | Uniprot | |
| K191 | Ubiquitination | Uniprot | |
| S193 | Phosphorylation | Uniprot | |
| K203 | Ubiquitination | Uniprot | |
| K204 | Ubiquitination | Uniprot | |
| S212 | Phosphorylation | Uniprot | |
| Y213 | Phosphorylation | Uniprot | |
| K222 | Ubiquitination | Uniprot | |
| K223 | Sumoylation | Uniprot | |
| K223 | Ubiquitination | Uniprot | |
| K230 | Ubiquitination | Uniprot | |
| K236 | Ubiquitination | Uniprot | |
| T242 | Phosphorylation | Uniprot | |
| T246 | Phosphorylation | Uniprot | |
| K248 | Acetylation | Uniprot | |
| K248 | Ubiquitination | Uniprot | |
| K250 | Ubiquitination | Uniprot | |
| S254 | Phosphorylation | Uniprot | |
| S260 | Phosphorylation | P31749 (AKT1) , Q15418 (RPS6KA1) , P23443 (RPS6KB1) | Uniprot |
| T261 | Phosphorylation | Uniprot | |
| K263 | Ubiquitination | Uniprot | |
| K272 | Acetylation | Uniprot | |
| K272 | Ubiquitination | Uniprot | |
| K278 | Ubiquitination | Uniprot | |
| K284 | Methylation | Uniprot | |
| K284 | Ubiquitination | Uniprot | |
| Y297 | Phosphorylation | Uniprot | |
| K342 | Ubiquitination | Uniprot | |
| K347 | Ubiquitination | Uniprot | |
| T379 | Phosphorylation | Uniprot | |
| S389 | Phosphorylation | Uniprot | |
| K402 | Ubiquitination | Uniprot | |
| S413 | Phosphorylation | Uniprot | |
| R427 | Methylation | Uniprot | |
| T428 | Phosphorylation | Uniprot | |
| K431 | Acetylation | Uniprot | |
| K431 | Ubiquitination | Uniprot | |
| S438 | Phosphorylation | Uniprot | |
| Y439 | Phosphorylation | Uniprot | |
| K441 | Acetylation | Uniprot | |
| K441 | Ubiquitination | Uniprot | |
| T448 | Phosphorylation | Uniprot | |
| Y456 | Phosphorylation | Uniprot | |
| S458 | Phosphorylation | Uniprot | |
| S470 | Phosphorylation | Uniprot | |
| K500 | Ubiquitination | Uniprot | |
| K522 | Ubiquitination | Uniprot | |
| K527 | Ubiquitination | Uniprot | |
| C535 | S-Nitrosylation | Uniprot |
研究背景
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin (Probable).
Cytoplasm.
Component of the chaperonin-containing T-complex (TRiC), a heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG. Interacts with FLCN.
Belongs to the TCP-1 chaperonin family.
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