Collagen VI alpha 3 Antibody - #DF13722
(2)
| 製品: | Collagen VI alpha 3 Antibody |
| カタログ: | DF13722 |
| タンパク質の説明: | Rabbit polyclonal antibody to Collagen VI alpha 3 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human |
| 予測: | Horse, Sheep |
| 分子量: | 343kDa; 344kD(Calculated). |
| ユニプロット: | P12111 |
| RRID: | AB_2846741 |
製品説明
ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human
予測:
Horse(100%), Sheep(100%)
クローナリティ:
Polyclonal
特異性:
Collagen VI alpha 3 Antibody detects endogenous levels of total Collagen VI alpha 3.
RRID:
AB_2846741
引用形式: Affinity Biosciences Cat# DF13722, RRID:AB_2846741.
引用形式: Affinity Biosciences Cat# DF13722, RRID:AB_2846741.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
CO6A3_HUMAN;COL6A3;Collagen alpha-3(VI) chain;Collagen type VI alpha 3;Collagen VI alpha 3;
免疫原
免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
- P12111 CO6A3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEITENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVCYLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT
種類予測
種類予測:
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
Species
Results
Score
Horse
100
Sheep
100
Dog
75
Pig
0
Bovine
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P12111 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T115 | Phosphorylation | Uniprot | |
| S162 | Phosphorylation | Uniprot | |
| S354 | Phosphorylation | Uniprot | |
| T433 | Phosphorylation | Uniprot | |
| T510 | Phosphorylation | Uniprot | |
| Y524 | Phosphorylation | Uniprot | |
| S540 | Phosphorylation | Uniprot | |
| Y543 | Phosphorylation | Uniprot | |
| S561 | Phosphorylation | Uniprot | |
| S934 | Phosphorylation | Uniprot | |
| S953 | Phosphorylation | Uniprot | |
| Y1072 | Phosphorylation | Uniprot | |
| K1156 | Acetylation | Uniprot | |
| S1225 | Phosphorylation | Uniprot | |
| K1231 | Acetylation | Uniprot | |
| K1305 | Ubiquitination | Uniprot | |
| Y1318 | Phosphorylation | Uniprot | |
| S1320 | Phosphorylation | Uniprot | |
| S1348 | Phosphorylation | Uniprot | |
| T1409 | Phosphorylation | Uniprot | |
| T1410 | Phosphorylation | Uniprot | |
| S1471 | Phosphorylation | Uniprot | |
| Y1493 | Phosphorylation | Uniprot | |
| S1512 | Phosphorylation | Uniprot | |
| S1654 | Phosphorylation | Uniprot | |
| S1737 | Phosphorylation | Uniprot | |
| S1783 | Phosphorylation | Uniprot | |
| T1929 | Phosphorylation | Uniprot | |
| S2048 | Phosphorylation | Uniprot | |
| N2079 | N-Glycosylation | Uniprot | |
| T2173 | Phosphorylation | Uniprot | |
| S2467 | Phosphorylation | Uniprot | |
| S2492 | Phosphorylation | Uniprot | |
| T2498 | Phosphorylation | Uniprot | |
| Y2641 | Phosphorylation | Uniprot | |
| S2652 | Phosphorylation | Uniprot | |
| N2677 | N-Glycosylation | Uniprot | |
| Y2767 | Phosphorylation | Uniprot | |
| S2821 | Phosphorylation | Uniprot | |
| Y2827 | Phosphorylation | Uniprot | |
| S2829 | Phosphorylation | Uniprot | |
| K2943 | Acetylation | Uniprot | |
| T2980 | Phosphorylation | Uniprot | |
| S3079 | Phosphorylation | Uniprot | |
| Y3142 | Phosphorylation | Uniprot |
研究背景
機能:
Collagen VI acts as a cell-binding protein.
PTMs:
Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
The N-terminus is blocked.
細胞の位置付け:
Secreted>Extracellular space>Extracellular matrix.
サブユニット構造:
Trimers composed of three different chains: alpha-1(VI), alpha-2(VI), and alpha-3(VI) or alpha-5(VI) or alpha-6(VI).
タンパク質ファミリー:
Belongs to the type VI collagen family.
研究領域
· Cellular Processes > Cellular community - eukaryotes > Focal adhesion. (View pathway)
· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > ECM-receptor interaction. (View pathway)
· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.
· Organismal Systems > Digestive system > Protein digestion and absorption.
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