Claudin 17 Antibody - #DF13751
| 製品: | Claudin 17 Antibody |
| カタログ: | DF13751 |
| タンパク質の説明: | Rabbit polyclonal antibody to Claudin 17 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse |
| 分子量: | 24kDa; 25kD(Calculated). |
| ユニプロット: | P56750 |
| RRID: | AB_2846770 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF13751, RRID:AB_2846770.
折りたたみ／展開
CLDN17; Human CLDN17 gene for claudin 17;
免疫原
In the kidney, expressed in the proximal tubule and in the Henle's loop. In the distal convoluted tubule, not expressed in all tubules. Not detected in the collecting duct (at protein level).
- P56750 CLD17_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAFYPLQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARVRLQCKFYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLGTSGVLFILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGGGLLCGFCCCNRKKQGYRYPVPGYRVPHTDKRRNTTMLSKTSTSYV
PTMs - P56750 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S38 | Phosphorylation | Uniprot | |
| Y202 | Phosphorylation | Uniprot |
研究背景
Channel-forming tight junction protein with selectivity for anions, including chloride and bicarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in quantitative reabsorption of filtered anions. Does not affect water permeability.
Cell junction>Tight junction. Cell membrane>Multi-pass membrane protein.
In the kidney, expressed in the proximal tubule and in the Henle's loop. In the distal convoluted tubule, not expressed in all tubules. Not detected in the collecting duct (at protein level).
Interacts with OCLN.
Belongs to the claudin family.
研究領域
· Cellular Processes > Cellular community - eukaryotes > Tight junction. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs). (View pathway)
· Human Diseases > Infectious diseases: Viral > Hepatitis C.
· Organismal Systems > Immune system > Leukocyte transendothelial migration. (View pathway)
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