Phospho-Claudin 5 (Tyr217) Antibody - #AF3935
| 製品: | Phospho-Claudin 5 (Tyr217) Antibody |
| カタログ: | AF3935 |
| タンパク質の説明: | Rabbit polyclonal antibody to Phospho-Claudin 5 (Tyr217) |
| アプリケーション: | IHC |
| 反応性: | Human, Mouse, Rat |
| 分子量: | 23kD(Calculated). |
| ユニプロット: | O00501 |
| RRID: | AB_2847658 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF3935, RRID:AB_2847658.
折りたたみ／展開
Androgen withdrawal and apoptosis induced protein RVP1 like; AWAL; BEC 1; BEC1; Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome); Claudin-5; Claudin5; CLD5_HUMAN; CLDN 5; Cldn5; CPETR L1; CPETRL 1; CPETRL1; TMDVCF; TMVCF; Transmembrane protein deleted in VCFS; Transmembrane protein deleted in velocardiofacial syndrome;
免疫原
A synthesized peptide derived from human Claudin 5 around the phosphorylation site of Tyr217.
- O00501 CLD5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKKNYV
PTMs - O00501 基板として
研究背景
Plays a major role in tight junction-specific obliteration of the intercellular space.
Cell junction>Tight junction. Cell membrane>Multi-pass membrane protein.
Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ (By similarity).
Belongs to the claudin family.
研究領域
· Cellular Processes > Cellular community - eukaryotes > Tight junction. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs). (View pathway)
· Human Diseases > Infectious diseases: Viral > Hepatitis C.
· Organismal Systems > Immune system > Leukocyte transendothelial migration. (View pathway)
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