Nuclear factor 1 C-type Antibody - #AF0022
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
Nuclear factor 1 C-type;NFIC;NF1-C;Nuclear factor 1/C;CCAAT-box-binding transcription factor;CTF;Nuclear factor I/C;NF-I/C;NFI-C;TGGCA-binding protein;NFIC;NFI;
免疫原
A synthesized peptide derived from human Nuclear Factor 1 C-type.
- P08651 NFIC_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MYSSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAEQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFVGLGPRDPAGIYQAQSWYLG
PTMs - P08651 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| S4 | Phosphorylation | Uniprot | |
| K58 | Ubiquitination | Uniprot | |
| K65 | Ubiquitination | Uniprot | |
| K99 | Ubiquitination | Uniprot | |
| K112 | Ubiquitination | Uniprot | |
| T146 | Phosphorylation | Uniprot | |
| S192 | Phosphorylation | Uniprot | |
| S194 | Phosphorylation | Uniprot | |
| T237 | Phosphorylation | Uniprot | |
| T270 | Phosphorylation | Uniprot | |
| S273 | Phosphorylation | Uniprot | |
| S275 | Phosphorylation | Uniprot | |
| S276 | Phosphorylation | Uniprot | |
| S277 | Phosphorylation | Uniprot | |
| S279 | Phosphorylation | Uniprot | |
| K280 | Acetylation | Uniprot | |
| S284 | Phosphorylation | Uniprot | |
| S286 | Phosphorylation | Uniprot | |
| T293 | Phosphorylation | Uniprot | |
| S294 | Phosphorylation | Uniprot | |
| Y299 | Phosphorylation | Uniprot | |
| T301 | Phosphorylation | Uniprot | |
| S302 | Phosphorylation | Uniprot | |
| S304 | Phosphorylation | Uniprot | |
| S305 | Phosphorylation | Uniprot | |
| T307 | Phosphorylation | Uniprot | |
| S310 | Phosphorylation | Uniprot | |
| T314 | Phosphorylation | Uniprot | |
| S322 | Phosphorylation | Uniprot | |
| S323 | Phosphorylation | Uniprot | |
| T328 | Phosphorylation | Uniprot | |
| S333 | Phosphorylation | Uniprot | |
| S337 | Phosphorylation | Uniprot | |
| S339 | Phosphorylation | Uniprot | |
| S343 | Phosphorylation | Uniprot | |
| R345 | Methylation | Uniprot | |
| T350 | Phosphorylation | Uniprot | |
| S361 | Phosphorylation | Uniprot | |
| R365 | Methylation | Uniprot | |
| S366 | Phosphorylation | Uniprot | |
| S371 | Phosphorylation | Uniprot | |
| R395 | Methylation | Uniprot | |
| S427 | Phosphorylation | Uniprot | |
| S438 | Phosphorylation | Uniprot | |
| R451 | Methylation | Uniprot | |
| T472 | Phosphorylation | Uniprot | |
| S473 | Phosphorylation | Uniprot | |
| S475 | Phosphorylation | Uniprot | |
| Y476 | Phosphorylation | Uniprot | |
| S477 | Phosphorylation | Uniprot | |
| T481 | Phosphorylation | Uniprot | |
| S482 | Phosphorylation | Uniprot | |
| S487 | Phosphorylation | Uniprot |
研究背景
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
Nucleus.
Binds DNA as a homodimer.
The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.
Belongs to the CTF/NF-I family.
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