Ascl2 Antibody - #DF13878
製品: | Ascl2 Antibody |
カタログ: | DF13878 |
タンパク質の説明: | Rabbit polyclonal antibody to Ascl2 |
アプリケーション: | ELISA(peptide) |
反応性: | Human, Mouse, Rat |
分子量: | 20kD; 20kD(Calculated). |
ユニプロット: | Q99929 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ/展開
Achaete scute complex like 2; Achaete scute homolog 2; achaete-scute complex-like 2; Achaete-scute homolog 2; ASCL2; ASCL2_HUMAN; ASH-2; Ash2; bHLHa45; Class A basic helix-loop-helix protein 45; HASH2; Mash2;
免疫原
A synthesized peptide derived from Human Ascl2.
Expressed specifically in the extravillous trophoblasts of the developing placenta.
- Q99929 ASCL2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDGGTLPRSAPPAPPVPVGCAARRRPASPELLRCSRRRRPATAETGGGAAAVARRNERERNRVKLVNLGFQALRQHVPHGGASKKLSKVETLRSAVEYIRALQRLLAEHDAVRNALAGGLRPQAVRPSAPRGPPGTTPVAASPSRASSSPGRGGSSEPGSPRSAYSSDDSGCEGALSPAERELLDFSSWLGGY
研究背景
AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
Nucleus.
Expressed specifically in the extravillous trophoblasts of the developing placenta.
Efficient DNA binding requires dimerization with another bHLH protein. Interacts with SETD1A. Part of a complex composed at least of ASCL2, EMSY, HCFC1, HSPA8, CCAR2, MATR3, MKI67, RBBP5, TUBB2A, WDR5 and ZNF335; this complex may have a histone H3-specific methyltransferase activity.
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