Hrk Antibody - #DF14002

(1)  
製品: Hrk Antibody
カタログ: DF14002
タンパク質の説明: Rabbit polyclonal antibody to Hrk
アプリケーション: IF/ICC
反応性: Human, Mouse, Rat
分子量: 10~20kD; 10kD(Calculated).
ユニプロット: O00198

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
Hrk Antibody detects endogenous levels of total Hrk.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

Activator of apoptosis harakiri; Activator of apoptosis Hrk; BCL2 interacting protein; BH3 interacting domain protein 3; BID3; DP5; Harakiri BCL2 interacting protein; Human brain 3UTR of mRNA for neuronal death protein partial sequence; Neuronal death protein DP5;

免疫原

免疫原:

A synthesized peptide derived from Human Hrk.

Uniprot:

O00198(HRK_HUMAN) >>Visit HPA database.

遺伝子(ID):
HRK(8739)
タンパク質配列:
MCPCPLHRGRGPPAVCACSAGRLGLRSSAAQLTAARLKALGDELHQRTMWRRRARSRRAPAPGALPTYWPWLCAAAQVAALAAWLLGRRNL

研究背景

機能:

Promotes apoptosis.

細胞の位置付け:

Membrane>Single-pass membrane protein. Mitochondrion.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with BCL2 and BCL2L1. Interacts with C1QBP.

タンパク質ファミリー:

The BH3 motif is required for the induction of cell death.

研究領域

· Cellular Processes > Cell growth and death > Apoptosis.   (View pathway)

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