Cytochrome b reductase 1 Antibody - #DF14043

(2)  
製品: Cytochrome b reductase 1 Antibody
カタログ: DF14043
タンパク質の説明: Rabbit polyclonal antibody to DCYTB
アプリケーション: WB IF/ICC
反応性: Human
分子量: 32kD; 32kD(Calculated).
ユニプロット: Q53TN4

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IHC Protocol
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製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
Cytochrome b reductase 1 Antibody detects endogenous levels of total Cytochrome b reductase 1.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

CYBR 1; CYBR1; CYBR1_HUMAN; CYBRD 1; cybrd1; Cytochrome b reductase 1; DCYTB; DKFZp564E227; Duodenal cytochrome b; Ferric chelate reductase 3; Ferric-chelate reductase 3; FLJ23462; FRRS3;

免疫原

免疫原:

A synthesized peptide derived from Human DCYTB.

Uniprot:

Q53TN4(CYBR1_HUMAN) >>Visit HPA database.

遺伝子(ID):
CYBRD1(79901)
発現特異性:
Q53TN4 CYBR1_HUMAN:

Present in erythrocyte membranes (at protein level). Also expressed in respiratory epithelium.

タンパク質配列:
MAMEGYWRFLALLGSALLVGFLSVIFALVWVLHYREGLGWDGSALEFNWHPVLMVTGFVFIQGIAIIVYRLPWTWKCSKLLMKSIHAGLNAVAAILAIISVVAVFENHNVNNIANMYSLHSWVGLIAVICYLLQLLSGFSVFLLPWAPLSLRAFLMPIHVYSGIVIFGTVIATALMGLTEKLIFSLRDPAYSTFPPEGVFVNTLGLLILVFGALIFWIVTRPQWKRPKEPNSTILHPNGGTEQGARGSMPAYSGNNMDKSDSELNSEVAARKRNLALDEAGQRSTM

研究背景

機能:

Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells.

細胞の位置付け:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Present in erythrocyte membranes (at protein level). Also expressed in respiratory epithelium.

研究領域

· Organismal Systems > Digestive system > Mineral absorption.

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