製品: GSTM1 Antibody
カタログ: DF14075
タンパク質の説明: Rabbit polyclonal antibody to GSTM1
アプリケーション: IHC IF/ICC
反応性: Human
分子量: 20~30kD; 26kD(Calculated).
ユニプロット: P09488

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 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
GSTM1 Antibody detects endogenous levels of total GSTM1.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Glutathione S alkyltransferase; Glutathione S aralkyltransferase; Glutathione S aryltransferase; Glutathione S transferase M1; Glutathione S transferase mu 1; Glutathione S transferase mu; Glutathione S-transferase Mu 1; GST class mu 1; GST class Mu; GST class-mu 1; GST HB subunit 4; GST mu; GST1; GSTM1 1; Gstm1; GSTM1-1; GSTM1_HUMAN; GSTM1a 1a; GSTM1a-1a; GSTM1b 1b; GSTM1b-1b; GTH4; GTM1; H B; HB subunit 4; MGC26563; MU 1; MU; S (hydroxyalkyl)glutathione lyase;

免疫原

免疫原:

A synthesized peptide derived from Human GSTM1.

Uniprot:
遺伝子(ID):
発現特異性:
P09488 GSTM1_HUMAN:

Liver (at protein level).

タンパク質配列:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK

研究背景

機能:

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Liver (at protein level).

サブユニット構造:

Homodimer.

タンパク質ファミリー:

Belongs to the GST superfamily. Mu family.

研究領域

· Human Diseases > Drug resistance: Antineoplastic > Platinum drug resistance.

· Human Diseases > Cancers: Overview > Pathways in cancer.   (View pathway)

· Human Diseases > Cancers: Overview > Chemical carcinogenesis.

· Human Diseases > Cancers: Specific types > Hepatocellular carcinoma.   (View pathway)

· Metabolism > Metabolism of other amino acids > Glutathione metabolism.

· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.

· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - cytochrome P450.

· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.

Restrictive clause

 

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