ATG101 Antibody - #DF14208
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ/展開
ATG101; Atg13-interacting protein; ATGA1_HUMAN; Autophagy-related protein 101; C12orf44; Chromosome 12 open reading frame 44; FLJ11773; OTTHUMP00000241687; OTTHUMP00000241688; OTTHUMP00000241689;
免疫原
A synthesized peptide derived from Human ATG101.
- Q9BSB4 ATGA1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNCRSEVLEVSVEGRQVEEAMLAVLHTVLLHRSTGKFHYKKEGTYSIGTVGTQDVDCDFIDFTYVRVSSEELDRALRKVVGEFKDALRNSGGDGLGQMSLEFYQKKKSRWPFSDECIPWEVWTVKVHVVALATEQERQICREKVGEKLCEKIINIVEVMNRHEYLPKMPTQSEVDNVFDTGLRDVQPYLYKISFQITDALGTSVTTTMRRLIKDTLAL
研究背景
Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation.
Cytoplasm. Preautophagosomal structure.
Note: Under starvation conditions, it is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation.
Interacts with ATG13. Associates with a complex composed of ATG13, ULK1 and RB1CC1; the association with this complex requires the presence of ATG13.
Belongs to the ATG101 family.
研究領域
· Cellular Processes > Transport and catabolism > Autophagy - other. (View pathway)
· Cellular Processes > Transport and catabolism > Autophagy - animal. (View pathway)
· Organismal Systems > Aging > Longevity regulating pathway. (View pathway)
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