SENP7 Antibody - #AF0278
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0278, RRID:AB_2833447.
折りたたみ／展開
KIAA1707; Senp7; SENP7_HUMAN; Sentrin specific protease; Sentrin-specific protease 7; Sentrin/SUMO-specific protease SENP7; SSP2; SUMO 1 specific protease 2; SUMO specific protease; SUMO-1-specific protease 2; SUMO1/sentrin specific peptidase 7; SUSP2;
免疫原
- Q9BQF6 SENP7_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLPLQWERSLRNKVISLDHKNKKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRKTLPRNDANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERIPRVILTNVLGTELGRKYIRTPPVTEGSLSDTDNLQSEQLSSSSDGSLESYQNLNPHKSCYLSERGSQRSKTVDDNSAKQTAHNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILRGHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSESALLELPLITCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGKIKGASKGCVTITKKYIKIPFQVSLNEISLLVDTTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYLQEIQTQLEHSVLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELELSYPLSWVQAFPLFQNLSSKESSFIHYYCVSTCSFPAGVAVAEEMKLKSVSQPSNTDAAKPTYTFLQKQSSGCYSLSITSNPDEEWREVRHTGLVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQQSQAQQSQNDNKTIDNDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILDSLKAASVQNTVQNLREYLEVEWEVKLKTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFKDPIVNFELPIHLEKWFPRHVIKTKREDIRELILKLHLQQQKGSSS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9BQF6 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S11 | Phosphorylation | Uniprot | |
| S12 | Phosphorylation | Uniprot | |
| S13 | Phosphorylation | Uniprot | |
| K20 | Methylation | Uniprot | |
| S24 | Phosphorylation | Uniprot | |
| S25 | Phosphorylation | Uniprot | |
| S46 | Phosphorylation | Uniprot | |
| R83 | Methylation | Uniprot | |
| K90 | Ubiquitination | Uniprot | |
| S92 | Phosphorylation | Uniprot | |
| K148 | Ubiquitination | Uniprot | |
| K321 | Ubiquitination | Uniprot | |
| K367 | Ubiquitination | Uniprot | |
| S373 | Phosphorylation | Uniprot | |
| S379 | Phosphorylation | Uniprot | |
| S407 | Phosphorylation | Uniprot | |
| K421 | Ubiquitination | Uniprot | |
| S433 | Phosphorylation | Uniprot | |
| S443 | Phosphorylation | Uniprot | |
| S444 | Phosphorylation | Uniprot | |
| K459 | Ubiquitination | Uniprot | |
| K537 | Ubiquitination | Uniprot | |
| K698 | Ubiquitination | Uniprot | |
| K710 | Ubiquitination | Uniprot | |
| S720 | Phosphorylation | Uniprot | |
| S721 | Phosphorylation | Uniprot | |
| K815 | Ubiquitination | Uniprot | |
| S916 | Phosphorylation | Uniprot | |
| K973 | Ubiquitination | Uniprot | |
| K1039 | Ubiquitination | Uniprot | |
| K1046 | Ubiquitination | Uniprot |
研究背景
Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms.
Belongs to the peptidase C48 family.
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