N myc interactor Antibody - #DF14405

(3)  
製品: N myc interactor Antibody
カタログ: DF14405
タンパク質の説明: Rabbit polyclonal antibody to N myc interactor
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
分子量: 35~40kD; 35kD(Calculated).
ユニプロット: Q13287

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MS Report
HPLC Report
MSDS
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WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
クローナリティ:
Polyclonal
特異性:
N myc interactor Antibody detects endogenous levels of total N myc interactor.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

N myc (and STAT) interactor; N myc and STAT interactor; N myc interactor; NMI; NMYC and STAT interactor; NMYC interactor;

免疫原

免疫原:

A synthesized peptide derived from Human N myc interactor.

Uniprot:

Q13287(NMI_HUMAN) >>Visit HPA database.

遺伝子(ID):
NMI(9111)
発現特異性:
Q13287 NMI_HUMAN:

Expressed in all adult and fetal tissues except brain and skin. More abundant in fetal tissues especially liver.

タンパク質配列:
MEADKDDTQQILKEHSPDEFIKDEQNKGLIDEITKKNIQLKKEIQKLETELQEATKEFQIKEDIPETKMKFLSVETPENDSQLSNISCSFQVSSKVPYEIQKGQALITFEKEEVAQNVVSMSKHHVQIKDVNLEVTAKPVPLNSGVRFQVYVEVSKMKINVTEIPDTLREDQMRDKLELSFSKSRNGGGEVDRVDYDRQSGSAVITFVEIGVADKILKKKEYPLYINQTCHRVTVSPYTEIHLKKYQIFSGTSKRTVLLTGMEGIQMDEEIVEDLINIHFQRAKNGGGEVDVVKCSLGQPHIAYFEE

研究背景

機能:

May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in all adult and fetal tissues except brain and skin. More abundant in fetal tissues especially liver.

サブユニット構造:

Interacts with MYCN and MYC, as well as with other transcription factors with a Zip, HLH or a HLH-Zip motif. Interacts with all STAT proteins except STAT2.

タンパク質ファミリー:

Belongs to the NMI family.

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